| 肿瘤靶向纳米递释系统存在问题的分析 |
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| 引用本文： | 李文清,邹豪,钟延强.肿瘤靶向纳米递释系统存在问题的分析[J].药学实践杂志,2015,33(2):106-109,170. |
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| 作者姓名： | 李文清 邹豪 钟延强 |
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| 作者单位： | 第二军医大学药学院药剂学教研室, 上海 200433,第二军医大学药学院药剂学教研室, 上海 200433,第二军医大学药学院药剂学教研室, 上海 200433 |
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| 摘 要： | 目的探究目前肿瘤靶向纳米递释系统存在的问题。方法在全面搜集查阅有关文献的基础上,对肿瘤靶向纳米递释系统研究现状进行归纳整理。结果从3个方面对肿瘤靶向纳米递释系统存在的问题以及新的发展趋势提出建议与对策。结论要在研究中取得突破,需要对人体生理学及肿瘤生物学进行深入研究,并在现有的给药策略和实验方法等方面进行调整。
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| 关 键 词： | 肿瘤靶向 纳米递释系统 主动靶向 PEG化 |
| 收稿时间： | 2014/1/14 0:00:00 |
| 修稿时间： | 2014/9/23 0:00:00 |
Analysis of problems on tumor-targeting drug delivery system |
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| LI Wenqing,ZOU Hao and ZHONG Yanqiang.Analysis of problems on tumor-targeting drug delivery system[J].The Journal of Pharmaceutical Practice,2015,33(2):106-109,170. |
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| Authors: | LI Wenqing ZOU Hao and ZHONG Yanqiang |
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| Institution: | Department of Pharmaceutics, School of Pharmacy, Second Military Medical University, Shanghai 200433, China,Department of Pharmaceutics, School of Pharmacy, Second Military Medical University, Shanghai 200433, China and Department of Pharmaceutics, School of Pharmacy, Second Military Medical University, Shanghai 200433, China |
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| Abstract: | Objective To analyze the current problems on tumor-targeting nanoparticle drug delivery system. Methods Recent researches of tumor-targeting nanoparticle drug delivery system were collected, read and summarized. Results Three research fields on tumor-targeting nanoparticle drug delivery system were reviewed in this article. Conclusion Not only a deeper understanding of the human physiology and tumor biology, but changes in strategies and experimental methods are needed to make new achievements on nanoparticle drug delivery system. |
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| Keywords: | tumor-targeting nanoparticle drug delivery system active targeting PEGylation |
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