陕西省2003年麻疹流行病学特征及健康人群麻疹抗体水平监测分析

为了解陕西省麻疹流行病学特征 ,评价健康人群麻疹抗体水平 ,对麻疹发病和实验室资料进行分析。结果显示 :陕西省 2 0 0 3年麻疹流行模式为爆发和散发并存 ,局部地区麻疹爆发影响着全省麻疹发病水平 ,发病年龄和免疫史状况说明 8月龄～ 7岁为高发年龄段 ,该年龄段病例麻疹疫苗 (MV)接种率为 4 3%。 4、5月为麻疹高发月 ,病例数占全年病例总数的 6 0 %。麻疹抗体水平监测结果显示 :2 0 0 3年健康人群麻疹抗体阳性率和几何平均滴度倒数 (GMRT)较 2 0 0 1年上升明显 ,处于较高水平。 2～ 4岁麻疹抗体GMRT较低。提示MV初种和复种均必须加强 ,有效接种率有待提高。应对 1 5～ 2岁儿童增加 1次MV免疫 ,8月龄～ 14岁儿童开展MV的强化免疫。

Analysis on Measles Epidemiology and Measles Antibody Levels Among Healthy Population in Shaanxi Province in 2003

In order to understand th e measles epidemiological characte ristics and evaluate measles antib ody levels among healthy population in Shaanxi Province,we analyzed the data on measles cases and laborato ry results.The results showed that both the sporadic and the outbreak meas les existed in the same time in 20 03.The outbreaks of measles in som e districts affected the measles m orbidity in the whole Province.The distribution status on the age gro up and the immunization history of measles vaccine(MV)indicated that the h igh incidence group was from 8 mont hs-6 years old,the coverage of MV in this group was only 43%.The peak period was April and May,meas les cases during this period accou nted for 60% of all measles cases in the whole year.The Measles anti body levels surveillance showed that the measles antibody GMRT and positive rate among healthy population in 2 003 was far higher than those in 2 001. Measles antibody GMRT among ch ildren aged 2-4 years old was lowe r.It suggested that MV primary imm unization and the second dose immu nization should be strengthened, an d the effective vaccination covera ge should be improved.The addition al dose of measles vaccination sho uld be given to the children aged 1 .5-2 years old and measles vaccine supplementary immunization should be conducted.