成人腹股沟区腹横筋膜胶原含量变化与腹股沟疝发病及复发的关系

目的：探讨腹股沟区横筋膜胶原含量变化与成人腹股沟疝发病及复发的关系，为临床工作提供理论参考。方法：以15例非疝成人作为对照组，成人腹股沟疝40例，斜疝组，直疝组13例，复发疝组11例，以氯胺－T法测定其腹股沟区腹横筋膜的胶原含量。分别探讨后者的改变与年龄的关系，比较疝组与对照组之间，以及各疝组之间的胶原含量。结果：正常成人腹磺筋膜的胶原含量与年龄呈负相关关系；疝病人中含量明显低于非疝病人；在疝病人中，胶原含量大小顺序为斜疝＞直疝＞复发疝＞结论：成人疝病人多为中，老年人，原因之一为随着年龄的增长 ，腹横筋膜中的胶原含量减少，抗张力强度降低。

Relationship between Reduction in Collagen Content of the Transverse Fascia and the Genesis/Recurrence of Inguinal Hernia

Chen Shuang,Zhu Liangmin,Fu Yuru.Department of General Surgery,Sun Yat sen Memorial Hospital of Sun Yat sen University of Medical Sciences,Guangzhou(510120)Objective:To investigate the relationship between reduction in collagen content of the transverse fascia(TF)and the genesis/recurrence of inguinal hernia.Methods:Forty patients with inguinal hernia,including16cases of indirect hernia(group I),13cases of direct hernia(group D)and11cases of recurrent hernia(group R)were studied.Fifteen healthy adults served as the control group.The collagen content specimens were determined by means of the method of dansyl chloride assay.The relationship between the age of the patients and the collagen content of inguinal TF was studied and compared among the groups.Results:The collagen content of inguinal TF was inversely correlated with the age in the control group,it was significantly higher in the controls than in the hernia patients.Among the patients of the hernia groups,the collagen content decreased according to the following order:group I>group D>group R.Conclusions:The increasing incidence and recurrence rate of inguinal hernia in patients with advanced age is attributable to a lowering in collagen content of the inguinal TF.