| 浙江七叶树种子中三萜皂苷成分的分离和鉴定* |
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| 引用本文： | 杨秀伟,郭杰.浙江七叶树种子中三萜皂苷成分的分离和鉴定*[J].中国新药杂志,2007,16(17):1373-1376. |
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| 作者姓名： | 杨秀伟 郭杰 |
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| 作者单位： | 1. 北京大学药学院天然药物及仿生药物国家重点实验室,北京,100083
2. 北京大学药学院天然药物及仿生药物国家重点实验室,北京,100083;北大世佳研究中心,北京,100084 |
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| 摘 要： | 目的:研究浙江七叶树Aesculus chinensis Bunge var.chekiangensis(Huet Fang)Fang种子中的化学成分。方法:采用大孔吸附树脂柱色谱、高效液相色谱等方法进行分离和纯化,根据化合物的谱学数据鉴定其结构。结果:从浙江七叶树种子的70%乙醇提取物中分离得到3个三萜皂苷类化合物,分别鉴定为七叶树皂苷(escins)IVe和IVh及七叶树皂苷(aesculuside)A。结论:这3个化合物皆为首次从浙江七叶树种子中分离得到。
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| 关 键 词： | 浙江七叶树 种子 三萜皂苷 |
| 文章编号： | 1003-3734（2007）17-1373-04 |
| 修稿时间： | 2007-02-10 |
Isolation and identification of triterpenoid saponins from seeds of Aesculus chinensis Bunge var. chekiangensis |
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| YANG Xiu-wei,GUO Jie.Isolation and identification of triterpenoid saponins from seeds of Aesculus chinensis Bunge var. chekiangensis[J].Chinese Journal of New Drugs,2007,16(17):1373-1376. |
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| Authors: | YANG Xiu-wei GUO Jie |
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| Institution: | 1. State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences ,Peking University, Beijing 100083, China; 2. Bescholor Research Center of Peking University, Beijing 100084, China |
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| Abstract: | Objective:To study the saponin constituents of the seeds of Aesculus chinensis Bunge var.chekiangensis(Hu et Fang)Fang.Methods:Compounds were separated and purified by macroreticular resin column chromatography and high-performance liquid chromatography.Their structures were elucidated by spectroscopic analysis.Results:Three compounds were isolated from the 70% ethanolic extracts.They were identified as escins IVe,IVh and aesculuside A.Conclusion:The above compounds were obtained from the seeds of A.chinensis Bunge var.chekiangensis(Hu et Fang)Fang for the first time. |
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| Keywords: | Aesculus chinensis Bunge var chekiangensis seed triterpenoid saponin |
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