| 糖尿病患者心率变异性与尿微量白蛋白排出的关系 |
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| 引用本文： | 姚媛,刘苔,马荣炜,张宏利.糖尿病患者心率变异性与尿微量白蛋白排出的关系[J].临床荟萃,2004,19(10):551-553. |
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| 作者姓名： | 姚媛 刘苔 马荣炜 张宏利 |
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| 作者单位： | 武警河北总队医院,内一科,河北,石家庄,050081 |
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| 摘 要： | 目的 探讨糖尿病自主神经病变对早期肾损害的影响。方法 30例早期糖尿病患者按不同尿微量白蛋白排出量(UAE)分为A(UAE正常)和B(UAE升高)两组．应用24小时动态心电图心率变异性(HRV)分析方法，检测其自主神经功能。结果 HRV时域指标(24小时相邻心搏的R-R间期之差大于50ms的心搏数每心搏总数的百分比、24小时相邻R—R间期差值的均方根值)及频域指标(夜间高频)B组均明显低于A组，且以反映迷走神经功能的夜间高频(HF)降低更为显著。结论 自主神经功能受损特别是迷走神经功能受损可能与糖尿病早期肾损害有关。
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| 关 键 词： | 糖尿病 蛋白尿 糖尿病神经病变 心率 |
| 文章编号： | 1004-583X(2004)10-0551-03 |
Relationship between heart rate variability and urinary albumin excretion in diabetic patients |
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| YAO Yuan,LIU Tai,MA Rong-wei,ZHANG Hong-li.Relationship between heart rate variability and urinary albumin excretion in diabetic patients[J].Clinical Focus,2004,19(10):551-553. |
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| Authors: | YAO Yuan LIU Tai MA Rong-wei ZHANG Hong-li |
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| Institution: | YAO Yuan,LIU Tai,MA Rong-wei,ZHANG Hong-liDepartment of Internal Medicine,Hebei Provincial Corps Hospital,Chinese People's Armed Police Forces,Shijiazhuang 050081,China |
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| Abstract: | Objective To study the effects of diabetic autonomic neuropathy on the early renal injury.Methods Thirty early diabetic patients were divided into group A(normal UAE) and B group(higher UAE) according to urinary albumin excretion(UAE).The cardiac autonomic function was tested by 24-hour electrocardiogram analysis of heart rate variability(HRV).Results PNN50, rMSSD in HRV time domain and nocturnal high frequency(HF) in HRV frequency domain showed more significant decrease in group B than in group A,and HF which reflects cardiac vagus function decreased more greatly.Conclusion The damage of vagus function in diabetic patients may be related to early renal injury. |
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| Keywords: | diabetes mellitus proteinuria diabetic neuropathy heart rate |
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