Increased recognition of IgA nephropathy in African-American children |
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| Authors: | Azra M. Sehic Lillian W. Gaber Shane Roy III Paula M. Miller Stephen B. Kritchevsky Robert J. Wyatt |
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| Affiliation: | (1) Division of Pediatric Nephrology, Department of Pediatrics, University of Tennessee, Memphis, and the Crippled Children’s Foundation Research Center at the Le Bonheur Children’s Medical Center, Memphis, Tennessee, USA, US;(2) Department of Pathology, University of Tennessee, Memphis, and the Crippled Children’s Foundation Research Center at the Le Bonheur Children’s Medical Center, Memphis, Tennessee, USA, US;(3) Division of Epidemiology, Department of Preventive Medicine, University of Tennessee, Memphis, and the Crippled Children’s Foundation Research Center at the Le Bonheur Children’s Medical Center, Memphis, Tennessee, USA, US |
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| Abstract: | Based upon the percentage of cases of IgA nephropathy (IgAN) in biopsy series, a lower prevalence has been assumed for African-Americans compared with Americans of European descent. This may be due to a racial difference in the basic underlying pathology of IgAN or to racial differences in patterns of referral and biopsy selection practices. Over the past decade (1985 – 1994), we have found similar incidences of IgAN in Caucasian and African-American children from Shelby County, Tennessee. The incidence was 3.0 cases per million per year for Caucasian and 5.7 cases per million per year for African-American children. IgAN may be more common in African-American children than previously appreciated. Population-based incidence studies will be necessary to determine whether or not our experience has become a more widespread phenomenon. Received August 21, 1996; received in revised form and accepted December 18, 1996 |
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| Keywords: | : IgA nephropathy Incidence African-American children |
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