过敏性哮喘患者血清中抗菌抗体的检测

采用改良双向琼脂扩散法,32例过敏性哮喘血清中有15例可检得细菌抗体,其中肺炎球菌的阳性率为31.25％,流感杆菌为18.75％,42例正常人仅6例阳性,肺炎球菌和流感杆菌均呈阴性。 细菌抗体检出率与能敏感反映炎症的血清C反应蛋白(CRP)值有关。13例CRP增高的过敏性哮喘中有11例可检得细菌抗体,表明细菌感染同样在过敏性哮喘中起一定作用。

THE DETECTION OF SERUM BACTERIAL PRECIPITINS IN ALLERGIC ASTHMATICS

Serum bacterial precipitins was detected by modified double immunodiffusion in 32 allergic asthmatics and 42 normal subjects.15 of 32 allergic asthmatics and 6 of 42 normal subjects showed positivity.The difference was very significant.The positive rate for Pneumococci and H.influenzae was respectively 31.25%,and 18.75% in asthmatics but both 0% in normal subjects.The positive rate of bacterial precipitins was relevant to the value of serum C reactive protein(CEP)which is the most sensitive indicator for the infection,11 of 13 cases with elevated serun CEP and 4 of 19 cases with normal CEP showed bacterial precipitins.The difference was also very significant.It has been suggested that the bacterial infection may play some role in allergic asthms.