3年中医院患者病原菌分布及耐药性分析

目的了解医院3年中病原菌的分布趋势及其耐药情况,以便合理地向临床提供抗菌药物应用策略。方法对3年临床送检标本,美国Dade Behring公司Microscan WalkAway-40全自动微生物分析仪进行菌株鉴定及药敏实验方法(微量MIC板)。结果近3年革兰阴性菌检出分别为252、507、742株,革兰阳性菌分别为142、166、243株,真菌依次为0、26、229株,革兰阴性菌主要为大肠埃希菌、肺炎克雷伯菌、铜绿假单胞菌、阴沟肠杆菌、鲍氏不动杆菌,革兰阳性菌为金黄色葡萄球菌、表皮葡萄球菌、溶血葡萄球菌、肠球菌属。结论了解常见病原菌分布及其耐药性对临床合理用药具有很重要的意义。

Distribution and Drug Resistance of Pathogens in a Hospital During Last Three Years

OBJECTIVE To investigate the distribution and resistance of commonly encountered pathogens,and provide reference of antimicrobial agents.METHODS For the clinical specimens during the last three years,flora identification and bacteriostatic test were operated with Microscan WalkAway-40.RESULTS Gram-negative bacteria were 252,507 and 742 strains,Gram-positive bacteria were 142,166,and 243 strains,fung were 0,26,and 229 strains from 2002 to 2004,respectively,the most commonly encountered Gram-negative bacteria were Escherichia coli,Klebsiella pneumoniae,Pseudomonas aeruginosa,Enterobacter cloacae,and Acinetobacter baumannii;the Gram positive bacteria were Staphylococcus aureus,S.epidermidis,S.haemolyticus,and Enterococcus.CONCLUSIONS It is important for reasonable drug application to know the distribution and resistance of commonly encountered bacteria.