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阿立哌唑与氯氮平治疗精神分裂症对照研究
引用本文:彭智勇,毛卫兰.阿立哌唑与氯氮平治疗精神分裂症对照研究[J].赣南医学院学报,2007,27(2):237-238.
作者姓名:彭智勇  毛卫兰
作者单位:宜春市第三人民医院,江西,宜春,336000;宜春市第三人民医院,江西,宜春,336000
摘    要:目的:探讨阿立哌唑与氯氮平对首发精神分裂症患者的临床疗效及安全性.方法:46例精神分裂症患者随机分为两组,分别给予阿立哌唑与氯氮平,治疗8周,用阳性与阴性症状表(PANSS)和副反应量表(TESS)评定疗效和不良反应.结果:阿立哌唑组疗效与氯氮平组疗效相当,阿立哌唑不良反应显著少于氯氮平.结论:阿立哌唑是一种安全有效的抗精神病药.

关 键 词:精神分裂症  阿立哌唑  氯氮平
文章编号:1001-5779(2007)02-0237-02
收稿时间:2006-10-20
修稿时间:2006年10月20

Comparative Study Between Aripiprazole and Clozapine in the Treatment of Schizophrenia
PENG Zhi-yong,MAO Wei-lan.Comparative Study Between Aripiprazole and Clozapine in the Treatment of Schizophrenia[J].Journal of Gannan Medical College,2007,27(2):237-238.
Authors:PENG Zhi-yong  MAO Wei-lan
Institution:The third Hospital of yichun,Yichun Jiangxi 336000
Abstract:Objective:To study the clinical efficacy and side effect of aripiprazole in the treatment of first-episode schizophrinia.Method: Forty-six schizophrenic patients were randomly divided into aripiprazole group and clozapine group for 8 weeks.PANSS and TESS were used to evaluate the efficacy and side effects respectively.Result:There were no significant difference in the total caraive effects between two groups(P>0.05).Aripiorazole had less side effects than clozapine did.Conclusion:Aripiprazole is a safe and effective antipcychotic drug.
Keywords:Schizophrenia  Aripiprazole  Clozapine
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