Complete response to chemoradiotherapy in a patient with synchronous double gastric and esophageal cancer |
| |
Authors: | Yoshida Naoki Kochi Mitsugu Fujii Masashi Kanamori Noriaki Kaiga Teruo Mihara Yoshiaki Funada Tomoya Tamegai Hidenori Watanabe Megumu Takayama Tadatoshi |
| |
Institution: | Department of Digestive Surgery, Nihon University School of Medicine, 30-1 Ohyaguchi Kamimachi, Itabashi-ku, Tokyo 173-8610, Japan. |
| |
Abstract: | A 77-year-old man with early synchronous double primary gastric and esophageal cancer showed complete response (CR) to chemoradiotherapy (CRT) with fluorouracil (5-FU) and cis-diamminedichloroplatinum (CDDP) and 60 Gy total dose of radiation. Gastrointestinal endoscopy had revealed type IIc squamous cell carcinoma in the lower oesophagus and type IIc adenocarcinoma in the mid-stomach region. Synchronous double primary early-stage esophageal and gastric cancer was diagnosed. The patient's age and chronic obstructive pulmonary disease (COPD) contraindicated radical esophageal surgery. Therefore, we decided to first administer CRT with 5-FU and CDDP for the esophageal cancer, and subsequently perform partial gastrectomy for the gastric cancer. After the CRT, neither of the tumors recurred. CR to CRT for the esophageal cancer and CR to chemotherapy for the gastric cancer were achieved. CONCLUSION: CRT with 5-FU and CDDP can produce CR in cases of early esophageal and gastric cancer. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|