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Low-frequency rTMS in the superior parietal cortex affects the working memory in horizontal axis during the spatial task performance
Authors:Jéssica Alves Ribeiro  Francisco Victor Costa Marinho  Kaline Rocha  Francisco Magalhães  Abrahão Fontes Baptista  Bruna Velasques  Pedro Ribeiro  Mauricio Cagy  Victor Hugo Bastos  Daya Gupta  Silmar Teixeira
Affiliation:1.Brain Mapping and Plasticity Laboratory,Federal University of Piauí,Parnaíba,Brazil;2.The Northeast Biotechnology Network (RENORBIO),Federal University of Piauí,Teresina,Brazil;3.Center for Mathematics, Computation and Cognition,Federal University of ABC,S?o Bernardo do Campo,Brazil;4.Brain Mapping and Sensorimotor Integration Laboratory,Federal University of Rio de Janeiro,Rio de Janeiro,Brazil;5.Brain Mapping and Functionality Laboratory,Federal University of Piauí,Parnaíba,Brazil;6.Department of Biology,Camden County College,Blackwood,USA
Abstract:Spatial working memory has been extensively investigated with different tasks, treatments, and analysis tools. Several studies suggest that low frequency of the repetitive transcranial magnetic stimulation (rTMS) applied to the parietal cortex may influence spatial working memory (SWM). However, it is not yet known if after low-frequency rTMS applied to the superior parietal cortex, according to Pz electroencephalography (EEG) electrode, would change the orientation interpretation about the vertical and horizontal axes coordinates in an SWM task. The current study aims at filling this gap and obtains a better understanding of the low-frequency rTMS effect in SWM. In this crossover study, we select 20 healthy subjects in two conditions (control and 1-Hz rTMS). The subjects performed an SWM task with two random coordinates. Our results presented that low-frequency rTMS applied over the superior parietal cortex may influence the SWM to lead to a larger distance of axes interception point (p?
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