山东东部地区女性喉癌患者的临床特点

目的 探讨山东东部地区女性喉癌患者的临床特点。 方法 对22例女性喉癌患者资料进行回顾性分析，其中声门上型8例，声门型13例，声门下型1例；按2002年AJCC标准进行分期：Ⅰ期10例，Ⅱ期2例，Ⅲ期4例，Ⅳ期6例。行喉部分切除术14例，喉全切除术6例，同时行颈清扫术10例，术后放疗10例。单纯放疗2例。生存率采用直接法计算。结果 行手术治疗的20例中，治疗后满3年者11例，失访2例，无瘤生存8例，3年直接生存率72.7%；治疗后满5年者6例，失访1例，无瘤生存5例，5年直接生存率83.3%；行单纯放射治疗的2例分别于治疗后9个月和1年死于复发。结论 女性喉癌发病率较低，声门上型喉癌构成比相对较高，部分女性喉癌患者与吸烟有关，女性喉癌患者的多原发癌值得重视

Clinical features of laryngeal carcinoma in females in the east of Shandong Province

Objective To investigate the clinical features of laryngeal carcinoma in females in the East of Shandong Province. Methods Twenty-two female patients with laryngeal carcinoma were retrospectively analyzed, including 8 cases of supraglottic carcinoma, 13 cases of glottic carcinoma and 1 case of subglottic carcinoma. According to AJCC（2002）, there were 10 cases in stageⅠ, 2 cases in stageⅡ,4 cases in stage Ⅲ, and 6 cases in stage Ⅳ. Partial laryngectomy was performed in 14 patients and total laryngectomy in 6 patients. 10 patients underwent neck dissection synchronously. Radiotherapy was performed in 10 patients after surgery. And 2 patients only received radiotherapy. The direct method was used to calculate the survival rate. Results Among the 20 patients who received surgery, 11 were followed up for more than 3 years: 2 were missed and 8 were disease-free survival. The 3-year survival rate was 72.7%. Only 6 patients were followed up for more than 5 years: 1 was missed and 5 were disease-free survived. The 5-year survival rate was 83.3%. The two patients who only received radiotherapy died because of the relapse in 9 months and 1 year after treatment respectively. Conclusion Laryngeal carcinoma in females has a low incidence. Supraglottic carcinoma is relatively common in female patients. Smoking is an important factor in some females. Multiple primary carcinomas should be focused on in females.