Effect of single-port video-assisted thoracoscopy on surgical site wound infection and healing in patients with lung cancer: A meta-analysis |
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Authors: | Wenqi Wu Yan Zhao Zhe Zhang Jingyuan Jiang Chong Feng Dongliang Qin Chen Zhang Zhenan Xu Lening Zhang Fengwu Lin |
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Institution: | 1. Department of Thoracic Surgery, China-Japan Union Hospital of Jilin University, Jilin, China;2. Physical Examination Center, The Second Hospital of Jilin University, Jilin, China |
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Abstract: | We performed a meta-analysis to comprehensively assess the effect of single-port video-assisted thoracoscopy on surgical site wound infection and healing in patients with lung cancer. A computerised search for studies on single-port video-assisted thoracoscopy treatment of lung cancer was conducted from the time of database creation through February 2023 using the PubMed, EMBASE, the Cochrane Library, China National Knowledge Infrastructure, and Wanfang databases. Two investigators independently screened the literature, extracted information, and evaluated the quality of studies according to inclusion and exclusion criteria. Either a fixed or random-effects model was used in calculating the relative risk (RR) with 95% confidence intervals (CIs). Meta-analysis was performed using RevMan 5.4 software. The results showed that, compared with multi-port video-assisted thoracoscopy, single-port video-assisted thoracoscopy significantly reduced surgical site wound infection (RR: 0.38, 95% CI: 0.19–0.77, P = .007) and significantly promoted wound healing (RR: 0.37, 95% CI: 0.22–0.64, P < .001). Compared with multi-port video-assisted thoracoscopy, single-port video-assisted thoracoscopy significantly reduced surgical site wound infections and also promoted wound healing. However, because of large variations in study sample sizes, some of the literature reported methods of inferior quality. Additional high-quality studies containing large sample sizes are needed to further validate these results. |
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Keywords: | meta-analysis single-port video-assisted thoracoscopy surgical site infection wound healing |
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