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Schizophrenia in autistic people with intellectual disabilities: Symptom manifestations and identification
Authors:Trine Lise Bakken  Arvid Nikolai Kildahl  Linn Beate Ludvigsen  Tale Gjertine Bjørgen  Caroline Dalhaug  Jane Margrete Askeland Hellerud  Oddbjørn Hove  Ann Magritt Solheim-Inderberg  Kjersti Karlsen  Sissel Berge Helverschou
Institution:1. Oslo University Hospital, Oslo Metropolitan University, Oslo, Norway;2. Oslo University Hospital, Oslo, Norway;3. Vestre Viken Hospital Trust, Gjettum, Norway;4. St. Olavs University Hospital, Norwegian University of Science and Technology, Trondheim, Norway;5. Helse Fonna Hospital Trust, Haugesund, Norway
Abstract:

Background

The assessment of schizophrenia in autistic people with intellectual disabilities is challenging. This study aimed to explore the identification of schizophrenia in this population.

Methods

Using data from a clinical multi-centre study, reported symptoms in 26 autistic individuals with intellectual disabilities diagnosed with co-occurring schizophrenia were explored. Scores on two checklists (Psychopathology in Autism Checklist PAC], Aberrant Behaviour Checklist ABC]) were compared with two comparison groups: autistic individuals with intellectual disabilities and other mental disorders (94), or no mental disorder (63).

Results

Reported symptoms of schizophrenia in this population met the formal diagnostic criteria. For PAC/ABC scales, only PAC psychosis differed for the schizophrenia group. Among participants with schizophrenia, two were diagnosed with additional mental disorders. Elevated scores for anxiety and depression were common.

Conclusions

Emphasising core symptoms seems necessary when assessing co-occurring schizophrenia in autistic people with intellectual disabilities. The PAC may serve as a helpful screening tool.
Keywords:autism spectrum disorder  diagnostic assessment  intellectual disabilities  schizophrenia
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