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Effect of honey dressing in the management of diabetic foot ulcers: A meta-analysis
Authors:Shaoting Li  Ting Xiao  Ning Ye  Guosheng Yang  Haiting Chen  Xia Liang  Tuodi Li  Jinying Wang  Yaozhong Peng  Yuan Li  Yanping Liu
Institution:1. Department of Pharmacy, the Fifth Hospital of Wuhan, Wuhan, Hubei, China;2. Department of Nephrology, the Fifth Hospital of Wuhan, Wuhan, Hubei, China;3. Department of Medical Examination Center, the Fifth Hospital of Wuhan, Wuhan, Hubei, China;4. Department of Emergency Medical Center, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China;5. Department of Nursing Department, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China;6. Department of General Surgery, the Fifth Hospital of Wuhan, Wuhan, Hubei, China;7. Department of Oncology, the Fifth Hospital of Wuhan, Wuhan, Hubei, China
Abstract:A meta-analysis study to assess the effect of honey dressing (HD) in the management of diabetic foot ulcer (DFU). A comprehensive literature examination till January 2023 was implemented and 1794 linked studies were appraised. The picked studies contained 882 subjects with DFUs were in the picked studies' baseline, 424 of them were using HD, and 458 were using a control. Odds ratio (OR) in addition to 95% confidence intervals (CIs) were used to calculate the consequence of HD in the management of DFUs after DFU by the dichotomous and continuous styles and a fixed or random model. The HD applied to DFUs caused a significantly higher wound healing rate (OR, 2.06; 95% CI, 1.45-2.93, P < .001) and lower wound healing time (MD, ?10.42; 95% CI, ?16.27- ?4.58, P < .001) compared with the control. The HD applied to DFUs caused a significantly higher wound healing rate and lower wound healing time compared with the control. Although precautions should be taken when commerce with the consequences since most of the picked studies for this meta-analysis was with low sample sizes.
Keywords:diabetic foot ulcer  honey dressing  wound healing rate  wound healing time
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