Induction of Bim and Bid gene expression during accelerated apoptosis in severe sepsis |
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| Authors: | Stefan U Weber Jens-Christian Schewe Lutz E Lehmann Stefan Müller Malte Book Sven Klaschik Andreas Hoeft Frank Stüber |
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| Institution: | Stefan U Weber, Jens-Christian Schewe, Lutz E Lehmann, Stefan Müller, Malte Book, Sven Klaschik, Andreas Hoeft, and Frank Stüber |
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| Abstract: | Introduction In transgenic animal models of sepsis, members of the Bcl-2 family of proteins regulate lymphocyte apoptosis and survival
of sepsis. This study investigates the gene regulation of pro-apoptotic and anti-apoptotic members of the Bcl-2 family of
proteins in patients with early stage severe sepsis. |
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