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Clinical efficacy of combined anti-Helicobacter treatment of patients with duodenal ulcer
Authors:Kirika N V  Bodrug N I  Butorov S I  Verbitskiĭ O N  Ridlovskiĭ A Iu  Butorov I V  Lagutkin D I  Martyniuk L I
Abstract:84 patients with duodenal ulcer and positive by Helicobacter pylori (HP) were divided into two groups. Group 1 consisted of 42 patients who received omeprasol, metranidasol and clarithromycin. Group 2 of 42 patients received rovamycin instead of clarythromycin. The results of the study show that anti-HP regimen with rovamycin is superior to clarythromycin by main criteria (percent of healed ulcers, HP eradication, time to remission, recurrence rate, side effects rate). Thus, three-component therapy of patients with recurrent duodenal ulcer maintains intragastric acidity optimal for fast healing of ulcer defect.
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