MMPI, personality dysfunction and the dexamethasone suppression test in major depression |
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Authors: | W H Norman G I Keitner I W Miller |
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Institution: | Department of Psychiatry and Human Behavior, Butler Hospital and Brown University, Providence, RI U.S.A. |
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Abstract: | In this study we examined the relationship of psychopathology and personality dysfunction to neuroendocrine functioning. MMPI profiles were examined for 30 psychiatric inpatients with major depression who were suppressors (60%) and nonsuppressors (40%) on the dexamethasone suppression test. There were no differences between suppressors and nonsuppressors on any of the MMPI scales or on DSM-III Axis-II diagnosis. When subdivided according to T-score elevations above 70 on MMPI scales 4 and 6, or 4 and 9, 30% of the sample, however, met criteria for personality dysfunction. Furthermore, a significantly higher proportion of suppressors (50%) evidenced personality dysfunction than did the nonsuppressors (8%). This suggests that certain MMPI scales are able to identify a subgroup of depressed patients with personality disturbances who also have a hypothalamic-pituitary-adrenal dysfunction. |
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Keywords: | Depression Dexamethasone suppression test (DST) MMPI Personality dysfunction |
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