依达拉奉联合苦碟子对急性脑梗死C反应蛋白和IL-6的影响 |
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引用本文: | 郑泽荣,黄敏,林风阳,刘晖,陈建强.依达拉奉联合苦碟子对急性脑梗死C反应蛋白和IL-6的影响[J].中医药研究,2009(7):789-790. |
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作者姓名: | 郑泽荣 黄敏 林风阳 刘晖 陈建强 |
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作者单位: | 广东省湛江市第二中医医院,524013) |
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基金项目: | 为2007年广东省湛江市科技立项课题(湛江市科技项目编号:2007C07022) |
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摘 要: | 目的探讨依达拉奉联合苦碟子对急性脑梗死患者血浆C反应蛋白(CRP)和白细胞介素-6(IL-6)水平的影响。方法92例急性脑梗死随机分为依达拉奉注射液联合苦碟子注射液治疗组(治疗组)和苦碟子注射液治疗组(对照组),治疗前和治疗2个疗程后测定血浆CRP和IL-6水平。结果两组患者治疗后,对照组和治疗组的CRP较治疗前分别地降低18.8%、46.7%,IL-6浓度较治疗前分别降低12.7%和9.6%,经统计学处理均有统计学意义(P〈0.05或P〈0.01)。结论依达拉奉联合应用苦碟子可通过降低CRP及IL-6水平来发挥保护脑组织作用。
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关 键 词: | 依达拉奉 苦碟子 急性脑梗死 C反应蛋白 白细胞介素-6 |
Effect of Edaravone with Kudiezi Injection on Plasma C - reactive Protein and lnterleukin - 6 in Acute Cerebral Infarction |
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Institution: | Zheng Zerong, Huang Min, Ltn Fengyang, et al (Zhanjiang Second Hospital of Traditional Chinese Medicine,Guangdong(Zhanjiang 524013)) |
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Abstract: | Objective To investigate the effect of edaravone with Kudiezi(ixeri sonhifolia) injection on plasma C- reactive protein (CRP) and interleukin- 6(IL-6) in patients(pts) with acute cerebral infarction(ACI). Methods Ninety- two pts with ACI were randomly divided into two groups:Treatment group treated by edaravone with Kudiezi injection and control group treated by Kudiezi injection. The levels of plasma CRP and IL - 6 were determined before and after treatment. Results After treatment, the levels of plasma CRP in treatment group and control group were decreased by 18.8% and 46.72% ,respectively,and plasma IL- 6 levels were decreased by 12.7% and 9.6% respectively(P〈0. 05 or P〈0.01). Conclusion Edaravone with Kudiezi injection had protective effect on brain tissue by lowering plasma CRP and IL - 6 levels. |
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Keywords: | edaravone Kudiezi injection acute cerebral infarction C- reactive protein interleukin- 6 |
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