结直肠手术后静脉血栓的发生与预防

目前,腹部外科手术后静脉血栓(VTE)的发病率逐年升高,VTE可导致静脉栓塞,严重者可引起致死性的肺栓塞。与其他腹部外科手术相比,结直肠手术患者术后发生VTE的风险更高,很多临床医师经常忽视这类患者术后血栓的预防。研究表明,使用低分子肝素或未分级肝素对结直肠患者进行术后的血栓预防,均能有效预防结VTE形成。低分子肝素因其使用次数少,不良反应少的特点被广泛使用。

The Risk and Prevention of Venous Thromboembolism after Colorectal Surgery

Nowadays,hospitalization for general abdominal surgery has a high risk of developing venous thromboembolism(VTE),a condition that encompasses both deep-vein thrombosis and its potentially fatal complication,pulmonary embolism.Colorectal surgery implies a specific high risk for postoperative VTE compared to other general surgery.The potential impact of VTE and the need for effective thromboprophylaxis are often underestimated in these patients.Prophylaxis with low-molecular-weight heparin or unfractionated heparin is recommended for colorectal surgery patients.Studies have shown that both low-molecular-weight heparin and unfractionated heparin can effectively reduce the incidence of VTE.Low-molecular-weight heparin has the practical advantage of once-daily administration and shows a lower risk of side effects..