Parvovirus B19 thrombocytopenic purpura complicated with a cerebral hemorrhage] |
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| Authors: | P Tourneux P Jouvencel M Micheau A C Jouvencel J F Chateil G Barba B Letavernier B Llanas |
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| Affiliation: | 1. Surgical Research Laboratory, Department of Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands;2. Department of Clinical Chemistry and Haematology, University of Utrecht, University Medical Center Utrecht, Utrecht, The Netherlands |
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| Abstract: | Severe hemorrhage complications are rare in idiopathic thrombocytopenic purpura. This pathology is often considered as benign. CASE REPORT: We report the case of a four-year-old boy presenting a parvovirus B19 idiopathic thrombocytopenic purpura. Despite early and repeated use of intravenous immunoglobulin, the evolution was characterized by the secondary apparition of a cerebral hemorrhage. It was lethal seven days after the initial diagnosis. CONCLUSION: Parvovirus B19 should be investigated as an etiologic agent of idiopathic thrombocytopenic purpura, using PCR. The unpredictive aspect of severe hemorrhage complications, especially cerebral hemorrhages, explains the potential severity of this disease. |
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