| 间接血凝试验在日本血吸虫病诊断中的价值研究 |
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| 引用本文： | 周杰,官威,危芙蓉,阮瑶,李胜明,许静,贾铁武,周晓农. 间接血凝试验在日本血吸虫病诊断中的价值研究[J]. 中国血吸虫病防治杂志, 2016, 28(4): 375-380. DOI: 10.16250/j.32.1374.2015252 |
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| 作者姓名： | 周杰 官威 危芙蓉 阮瑶 李胜明 许静 贾铁武 周晓农 |
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| 作者单位： | 1 湖南省血吸虫病防治所 （岳阳 414000）； 2 中国疾病预防控制中心寄生虫病预防控制所 |
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| 基金项目： | 中英全球卫生支持项目(GHSP-OP101);湖南省科技厅项目(2012FJ4103) |
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| 摘 要： | 目的评价间接血凝试验(IHA)在日本血吸虫病诊断中的应用价值。方法在Medline、中国知网、维普、万方数据库中收集1982-2014年有关IHA诊断日本血吸虫病的相关研究文献,采用Meta分析法进行评价。结果有21篇符合要求的文献纳入本研究。在实验室评估中,IHA法检测日本血吸虫病AUCSROC=0.990 6;但在现场应用中,AUCSROC=0.832 9;两者差异有统计学意义(Z=4.50,P0.05)。结论 IHA在现场应用中的日本血吸虫病诊断价值低于在实验室评估中的诊断价值。在消除血吸虫病阶段,亟待开发现场应用价值高的诊断试剂。
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| 关 键 词： | 日本血吸虫病； 间接血凝试验； Meta分析； 免疫诊断 |
Study on value of IHA in diagnosis of schistosomiasis japonicaObjective |
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| ZHOU Jie;GUAN Wei;WEI Fu-rong;RUAN Yao;LI Sheng-ming;XU Jing;JIA Tie-wu;ZHOU Xiao-nong. Study on value of IHA in diagnosis of schistosomiasis japonicaObjective[J]. Chinese journal of schistosomiasis control, 2016, 28(4): 375-380. DOI: 10.16250/j.32.1374.2015252 |
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| Authors: | ZHOU Jie GUAN Wei WEI Fu-rong RUAN Yao LI Sheng-ming XU Jing JIA Tie-wu ZHOU Xiao-nong |
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| Affiliation: | 1.Hunan Provincial Institute of Schistosomiasis Control|Yueyang 414000|China；2 National Institute of Parasite Diseases|Chi? nese Center for Disease Control and Prevention |
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| Abstract: | Objective To evaluate the value of indirect hemagglutination test（IHA）in schistosomiasis diagnosis. Meth Meth? ? ods ods The literature concerned schistosomiasis diagnosis with IHA in the databases of Medline，CNKI，VIP and Wanfang Data from 1982 to 2014 was collected and evaluated. Results Results Totally 21 articles which were satisfied with the research criteria were analyzed with the Meta?analysis method. The IHA method had high value in schistosomiasis diagnosis，the AUCSROC of IHA in laboratory evaluation was 0.990 6，while in filed evaluation was 0.832 9，and the difference between them was significant（Z = 4.50，P < 0.05） . Conclusion Conclusion The diagnosis value of IHA in field evaluation is less than that in laboratory. In the process of the elimination of schistosomiasis，developing a new and higher sensitive reagent in schistosomiasis diagnosis is needed. |
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| Keywords: | Schistosomiasis japonica；IHA；Meta?analysis；Immunodiagnosis |
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