急性冠脉综合征患者冠脉介入术后无复流现象的影响因素探讨

目的探讨经皮冠状动脉介入治疗（PCI）后冠脉无复流现象发生的影响因素。方法回顾性分析因急性冠脉综合征入我院行PCI治疗患者380例,PCI支架置入即刻,冠状动脉造影前向血流TIMI≤2级为无复流,TIMI3级为正常血流,利用Excel随机函数表,从380例急诊PCI冠状动脉前向血流恢复正常的患者中随机抽取70例为对照组。结果冠状动脉无复流患者35例,无复流组急性心肌梗死（AMI）比例明显高于对照组（P〈0.05）;无复流组和对照组在PCI术后的造影结果中观察到在发生以下结果的例数方面差异有显著性（P〈0.05）：几乎完全闭塞、血栓、钙化、长病变,而在其它评价指标的例数差异无显著性（P〉0.05）。结论急性心肌梗死、白细胞水平以及冠状动脉特殊病变形态（几乎完全闭塞、血栓、钙化、长病变）与无复流现象发生有一定关系。

Analysis of Influencing Factors in No-Reflow Phenomenon of Patients with Acute Coronary Syndrome after Percutaneous Coronary Intervention

Objective： To evaluate the influencing factors in no-reflow phenomenon after percutaneous coronary intervention （PCI）.Methods： 380 patients with acute coronary syndrome were admitted in our prognostic analysis. All patients underwent primary PCI,stenting immediately,the blood flow TIMI≤ 2 for no-reflow,TIMI 3 for normal. We selected 70 for the control group from patients with normal blood flow after primary PCI using the random Excel table.Result： 35 of all patients for no-reflow phenomenon group,the ratio of patients was higher in it than that in the control group （P〈0.05）; And the ratio of patients was higher in no-reflow phenomenon group than that in the control group （P〈0.05） in coronary artery form such as almost complete occlusion,thrombosis,calcification and long lesions, but it showed no significant difference（P〉0.05） in other evaluation. Conclusion： The occurrence of no-reflow phenomenon show a certain relationship with factors such as acute myocardial infarction, leukocyte level and the special form of coronary artery （almost complete occlusion, thrombosis, calcification, long lesions）.