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| 补肾安胎方对肾虚流产大鼠子宫蜕膜Th1/Th2细胞因子的影响 | |
| 引用本文： | 刘红霞,姚静,刘芳.补肾安胎方对肾虚流产大鼠子宫蜕膜Th1/Th2细胞因子的影响[J].深圳中西医结合杂志,2011,21(2):69-71,90. |
| 作者姓名： | 刘红霞 姚静 刘芳 |
| 作者单位： | 1. 湖南省冷水江市中医院,湖南,冷水江,417500 2. 深圳市第二中医院,广东,深圳,518034 3. 深圳市妇幼保健院,广东,深圳,518028 |
| 摘 要： | 目的：研究补肾安胎方对肾虚流产模型大鼠子宫蜕膜上Th1/Th2型细胞因子的影响。方法：SPF级SD大鼠随机分为3组,每组15只。A组为肾虚流产模型组,用羟基脲加米非司酮灌服;B组为补肾安胎方干预组,用羟基脲加米非司酮加补肾安胎方水提液灌服;C组灌服生理盐水。酶联免疫法检测子宫蜕膜组织的Th1型细胞因子IL-2和Th2型细胞因子IL-10浓度。结果：3组子宫蜕膜IL-2、IL-10浓度和IL-2/IL-10比值比较,差异有统计学意义（P〈0.01）;A、B组的IL-2显著高于C组（P均〈0.01）,A组与B组的IL-2比较差异无统计学意义（P〉0.05）;B组的IL-10显著低于C组（P〈0.01）,A组的IL-10显著高于C组（P〈0.01）,A组与C组的IL-10比较差异无统计学意义（P〉0.05）;IL-2/IL-10比值比较A组显著高于B组（P〈0.01）,与C组比较无显著差异（P〉0.05）。结论：补肾安胎方能促进大鼠子宫蜕膜Th2型细胞因子IL-10的分泌,扭转Th1/Th2细胞因子病理性失衡,降低肾虚流产大鼠模型的流产率。 |
| 关 键 词： | 补肾安胎方 流产模型 肾虚 大鼠 Th1/Th2细胞因子 |
Effect of BUSHENANTAIFANG on Th1/Th2 Cytokines in Uterine Decidua of Abortion Rat with Kidney Deficiency |
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| LIU Hong-xia,YAO-Jing,LIU Fang.Effect of BUSHENANTAIFANG on Th1/Th2 Cytokines in Uterine Decidua of Abortion Rat with Kidney Deficiency[J].Shenzhen Journal of Integrated Traditional Chinese and Western Medicine,2011,21(2):69-71,90. | |
| Authors: | LIU Hong-xia YAO-Jing LIU Fang |
| Institution: | LIU Hong-xia1,YAO-Jing2,LIU Fang3(1.Hunan Lengshui Traditional Chinese Medical Hospital,Hunan Lengshui 417500,2.Shenzhen Second Traditional Chinese Medical Hospital,Guangdong Shenzhen 518034,3.Shenzhen Maternal and Child Health Hospital,Guangdong Shenzhen 518028) |
| Abstract: | Objective To investigate the effect of BUSHENANTAIFANG on Th1/Th2 cytokines in uterine decidua of abortion model rat with Kidney Deficiency.Methods SPF SD rats were randomly divided into 3 groups:Group A was the model of abortion with Kidney Deficiency and were given hydroxyurea and Mifepristone;Group B was experiment group treated with BUSHENANTAIFANG and were given hydroxyurea,Mifepristone and BUSHENANTAIFANG;Group C was given NS as control.IL-2 and IL-10 in Uterine decidua were detected by Enzyme-linked ... |
| Keywords: | BUSHENANTAIFANG Abortion model Kidney deficiency Rat Th1/Th2 cytokines |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |