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血清C反应蛋白和同型半胱氨酸与冠心病相关性研究
引用本文:佘吉佳,李卓成.血清C反应蛋白和同型半胱氨酸与冠心病相关性研究[J].深圳中西医结合杂志,2011,21(2):77-79.
作者姓名:佘吉佳  李卓成
作者单位:深圳市第二人民医院检验科,广东,深圳,518035
摘    要:目的:探讨冠心病(CHD)患者血清C反应蛋白(CRP)和同型半胱氨酸(HCY)的水平与冠状动脉病变程度的关系。方法:80例经冠状动脉造影确认的CHD患者,急性心肌梗死(AMI)24例、不稳定型心绞痛(UAP)30例、稳定型心绞痛(SAP)26例。选40例健康者为对照。另根据动脉造影结果将80例CHD患者分为单支病变组(20例)、双支病变组(34例)、三支病变组(26例)。分别采集外周静脉血同时检测CRP和HCY的水平进行分析。结果:CHD患者血清CRP和HCY的水平与健康组相比显著增高(P〈0.01)。AMI、UAP、SAP三组相比较CRP和HCY的水平依次降低,两两比较差异有统计学意义(P〈0.05)。CHD患者血清CRP和HCY的水平在冠状动脉单支病变、双支病变、三支病变组依次增高,两两比较差异有统计学意义(P〈0.05)。结论:血清CRP和HCY的水平与冠状动脉病变程度及病变支数有关,提示血清CRP和HCY可作为冠状动脉病变程度的诊断依据。

关 键 词:冠心病  C反应蛋白  同型半胱氨酸

Study on the Association between Serum C Reactive Protein or Homocysteine and Coronary Heart Disease
SHE Ji-jia,LI Zhuo-cheng.Study on the Association between Serum C Reactive Protein or Homocysteine and Coronary Heart Disease[J].Shenzhen Journal of Integrated Traditional Chinese and Western Medicine,2011,21(2):77-79.
Authors:SHE Ji-jia  LI Zhuo-cheng
Institution:SHE Ji-jia,LI Zhuo-cheng*(Department of Clinical Laboratory of Shenzhen Second Hospital,Guangdong Shenzhen,518035)
Abstract:Objective To investigate the relationship between serum C reactive Protein(CRP) or Homocysteine(HCY) level and severity of coronary artery disease in patients with coronary heart disease(CHD).Methods 80 patients were diagnosed as CHD by coronary angiography in which there were 24 patients with acute myocardial infarction(AMI)(AMI group),30 cases with unstable angina pectoris(UAP)(UAP group),26 cases with stable angina pectoris(SAP)(SAP group) and 40 healthy persons(NC group).In addition,according to the num...
Keywords:C reactive protein  Homocysteine  Coronary heart disease  
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