| 抑郁症患者吸烟对马普替林治疗作用的影响 |
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| 引用本文： | 安庆华,罗维玲,李从梅. 抑郁症患者吸烟对马普替林治疗作用的影响[J]. 四川精神卫生, 2005, 18(1): 25-26 |
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| 作者姓名： | 安庆华 罗维玲 李从梅 |
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| 作者单位： | 256613,山东省滨州市人民医院精神卫生中心;256613,山东省滨州市人民医院精神卫生中心;256613,山东省滨州市人民医院精神卫生中心 |
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| 摘 要： | 目的探讨抑郁症患者吸烟对马普替林治疗剂量、疗效和不良反应的影响。方法对120例符合CCMD-3诊断标准的抑郁症患者，采用HAMD量表减分率评价其临床疗效，用TESS评定其安全性。对吸烟和不吸烟的抑郁症患者进行马普林治疗剂量、疗效和不良反应的比较。结果吸烟的抑郁症患者所服马普替林日平均剂量显著高于不吸烟的患者、疗效显著差于不吸烟患者，不良反应显著轻于不吸烟患者。结论抑郁症患者在马普替林治疗期间少吸烟或不吸烟，可以减少马普替林的用量和提高疗效。
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| 关 键 词： | 抑郁症 马普替林 吸烟 |
| 文章编号： | 1007-3256(2005)01-0025-02 |
Smoking patients with depression have an influence on the therapeutic effect of maprotiline |
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| AN Qinghu a,LUO Weiling,LI Congmei. Smoking patients with depression have an influence on the therapeutic effect of maprotiline[J]. Sichuan Mental Health, 2005, 18(1): 25-26 |
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| Authors: | AN Qinghu a LUO Weiling LI Congmei |
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| Affiliation: | AN Qinghu a,LUO Weiling,LI Congmei.Binzhou Mental Health Center,Shandong 256613,China |
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| Abstract: | Objective To study the influence between smoking and t herapeutic dosage,side effects of maprotiline in depressive patients. Methods 120 inpatients who met criteria of depression in CCMD-3 were adopted.The clinical effect was evaluated by reduced rate of HAMD.The safety wa s evaluated by TESS.The dosage,therapeutic efficacy and side effects of maprotil ine in smoking patients were compared with nonsmoking patients.Result s The effective dosage of maprotiline was higher in smoking patients than in nonsmoking patients,the efficacy was more significantly in nonsmoking p atients.Conclusion During treatment with maprotiline,smok ing should be forbidden as far as possible in depression.This procedure can decr ease dosage of maprotiline and enhance the effect of maprotiline. [ |
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| Keywords: | Depression Maprotiline Smoking |
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