Effect of epithermal neutrons on viability of glioblastoma tumor cells in vitro |
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Authors: | Mostovich L A Gubanova N V Kutsenko O S Aleinik V I Kuznetsov A S Makarov A N Sorokin I N Taskaev S Yu Nepomnyashchikh G I Grigor'eva E V |
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Affiliation: | (1) Nuclear Engineering Teaching Lab, PRC-9000, University of Texas at Austin, Texas 78712, USA |
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Abstract: | We studied in vitro effect of epithermal neutrons in various doses on viability of glioblastoma U87 tumor cells. Increasing the dose from 1.9 to 4.1 Sv promoted cell death. Cytofluorimetric analysis revealed no activation of apoptosis in the irradiated cells, which attested to necrotic death of the tumor cells exposed to epithermal neutron radiation. |
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