保乳手术与改良根治术对早期乳腺癌患者预后及生活质量的临床观察

目的比较保乳手术与改良根治术对早期乳腺癌（临床Ⅰ、Ⅱ期）患者的预后及生活质量的差别。方法回顾我院诊治的180例早期乳腺癌，分为保乳组与改良组，各90例。2组术后均按适应证进行放疔、化疗及内分泌治疗，观察其预后及生活质量的差别。结果患者均术后随访5年，2组的无病生存期差异无统计学意义，但保乳组的生活质量（总体健康、生理功能、生理职能、躯体疼痛、活力、社会功能、情感职能及精神健康）明显高于改良组。结论对早期乳腺癌患者应用保乳手术治疗，效果理想，且能取得良好的美容效果，提高生活质量，临床可积极应用。

Prognosis and life quality of patients undergoing breast-conserving surgery or modified radical mastectomy

Objective To compare the prognosis and life quality of patients with early-stage breast cancer （stage l or Ⅱ） undergoing breast-conserving surgery or modified radical masteetomy. Methods 180 cases with early-stage breast cancer were divided into 2 groups： breast-conserving surgery group （BCS） and modified radical mastectomy group （MRM） , with 90 cases in each group, The 2 groups were all given radiotherapy, chemotherapy and endocrine therapy according to indications. The prognosis and life quality in the 2 groups were compared. Results The 5-year-postoperative follow-up showed there was no significant difference in duration of disease-free survival （DFS） of the 2 groups. However, life quality of BCS patients was significantly better than that of MRM patients in terms of general health, physical function, pain, vitality, social functioning, emotion and mental health. Conclusion Breast-conserving surgery is highly recommended for patients with early-stage breast cancer.