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变应性支气管肺曲霉菌病的临床特征
引用本文:叶茂斌,刘登华,郭瑞敏,张临洪,谢俊刚,徐永健,唐荣华. 变应性支气管肺曲霉菌病的临床特征[J]. 内科急危重症杂志, 2013, 0(6): 336-337,341
作者姓名:叶茂斌  刘登华  郭瑞敏  张临洪  谢俊刚  徐永健  唐荣华
作者单位:华中科技大学同济医学院附属同济医院,武汉430030
摘    要:目的:分析我院变应性支气管肺曲霉菌病(ABPA)的临床特征,为临床诊断及治疗提供帮助.方法:回顾性分析诊断为ABPA 8例患者的临床资料.结果:8例ABPA患者临床表现主要为咳嗽、胸闷、喘息.6例有肺部慢性疾病史,肺部CT特征性表现为囊状支气管扩张及黏液栓.结论:对于临床可疑ABPA患者,查血清总IgE及曲霉菌特异性IgE,行曲霉菌变应原皮肤点刺试验和纤维支气管镜检查有助于明确诊断.治疗以激素加抗真菌药物为主.

关 键 词:变应性支气管肺曲霉菌病  哮喘  免疫球蛋白E

Clinical features of allergic bronchopulmonary aspergillosis
YE Mao-bin,LIU Deng-hua,GUO Rui-min,ZHANGLin-hong,XIE Jun-gang,XU Yong-jian,TANG Rong-hua. Clinical features of allergic bronchopulmonary aspergillosis[J]. Journal of Internal Intensive Medicine, 2013, 0(6): 336-337,341
Authors:YE Mao-bin  LIU Deng-hua  GUO Rui-min  ZHANGLin-hong  XIE Jun-gang  XU Yong-jian  TANG Rong-hua
Affiliation:. Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030 , China
Abstract:Objective: To analyze the clinical features of allergic bronchopuhnonary aspergillosis (ABPA) in order to provide aid for clinical diagnosis and treatment. Methods : Clinical data of 8 cases with ABPA were analyzed retrospectively. Results: The main clinical manifestations were cough, chest tightness and asthma. Six cases had a history of chronic lung disease. Cystic bronchiectasis and mucus plug were the characteristic manifestations of CT in the lung. Conclusion: For patients with clinical suspicion of ABPA, detection of serum ASP-specific IgE and total IgE, skin prick test as well as fiberoptic bronchoscopy are helpful to clarify the diagnosis. Steroid and antifnngal drugs are the main treatments.
Keywords:Allergic bronchopulmonary aspergillosis Asthma lmmunoglobulin E
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