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奎硫平治疗精神分裂症临床观察
引用本文:姚辉,侯钢,王筱兰,尚晓芳,袁勇贵.奎硫平治疗精神分裂症临床观察[J].临床精神医学杂志,2003,13(5):273-274.
作者姓名:姚辉  侯钢  王筱兰  尚晓芳  袁勇贵
作者单位:210029,南京医科大学附属脑科医院
摘    要:目的:探讨奎硫平治疗精神分裂症的疗效及安全性。方法:奎硫平治疗精神分裂症31例。采用阳性症状与阴性症状量表(PANSS)、副反应量表(TESS)和锥体外系副反应量表(ESRS)评定疗效及不良反应。结果:奎硫平治疗精神分裂症有效率93.5%,显效率71.0%,无明显锥外系反应。结论:奎硫平治疗精神分裂症疗效确切,不良反应少。

关 键 词:奎硫平  精神分裂症  疗效  安全性
文章编号:1005-3220(2003)05-0273-02
修稿时间:2003年6月19日

A clinical trial of quetiapine in the treatment of schizophrenic patients
Yao Hui,Hou Gang,Wang Xiaolan,et al..A clinical trial of quetiapine in the treatment of schizophrenic patients[J].Journal of Clinical Psychological Medicine,2003,13(5):273-274.
Authors:Yao Hui  Hou Gang  Wang Xiaolan  
Institution:Yao Hui,Hou Gang,Wang Xiaolan,et al.Department of Psychiatry,the Affiliated Brain Hospital of Nanjing Medical University,Nanjing 210029
Abstract:Objective:To study the efficacy and toxicity of quetiapine in the treatment of schizophrenic patients. Method:Thirty-one schizophrenic patients were treated with quetiapine. The efficacy was measured with the positive and negative symptoms scale (PANSS),while the adverse events were determined by the treatment emergent symptoms scale (TESS) and extrapyramidal symptom rating scale (ESRS). Results:The efficacy rate of quetiapine was 93.5%, in which 71.0% were improved markedly. 6.5% of subjects demonstrated extrapyramidal side effects. Conclusion:Quetiapine is effective for both positive and negative symptoms of schizophrenia.
Keywords:Quetiapine  Schizophrenia  Efficacy  Safety
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