| 深绿山龙眼中二个新的植物脑苷的结构鉴定 |
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| 引用本文： | 吴彤,孔德云,李惠庭. 深绿山龙眼中二个新的植物脑苷的结构鉴定[J]. 药学学报, 2004, 39(7): 525-527 |
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| 作者姓名： | 吴彤 孔德云 李惠庭 |
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| 作者单位： | 上海医药工业研究院,上海,200040 |
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| 摘 要： | 目的研究深绿山龙眼Helicia nilagirica的化学成分。方法应用硅胶柱色谱法对深绿山龙眼叶子的化学成分进行分离,根据理化常数测定和光谱分析鉴定化合物的结构。结果得到2个植物脑苷化合物:Helicia cerebrosides A(1)和B(2)。确定了1的结构,并初步推定2的结构。结论化合物1和2为新的植物脑苷化合物。
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| 关 键 词： | 深绿山龙眼 植物脑苷 Helicia cerebroside A Helicia cerebroside B |
| 收稿时间： | 2003-08-22 |
Structure identification of two new cerebrosides from Helicia nilagirica Beed. |
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| WU Tong,KONG De-yun,LI Hui-ting. Structure identification of two new cerebrosides from Helicia nilagirica Beed.[J]. Acta pharmaceutica Sinica, 2004, 39(7): 525-527 |
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| Authors: | WU Tong KONG De-yun LI Hui-ting |
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| Affiliation: | Shanghai Institute of Pharmaceutical Industry, Shanghai 200040, China. Tongwu8@hotmail.com |
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| Abstract: | AIM: To study the bioactive components from Helicia nilagirica. METHODS: Compounds were separated with a combination of multi-chromatography. Their chemical structures were determined on the basis of spectral analysis and chemical evidence. RESULTS: Two compounds were isolated from the leaves of Helicia nilagirica. Compound 1 was elucidated as 1-O-3-D-glucopyranosyl-(2S,3S,4R,8Z)-2-[(2'R)-2'-hyd roxylignocenoyl-amino]-8-octadecene-1, 3, 4-triol. Compound 2 was an analogue of 1. CONCLUSION :The two compounds are new cerebrosides. |
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| Keywords: | Helicia nilagirica Beed. cerebrosides Helicia cerebroside A Helicia cerebroside B |
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