新生儿缺氧缺血性脑病的MRI表现

目的：分析新生儿缺氧缺血性脑病（HIE）的MRI表现特点。材料与方法：采用永磁型低场磁共振成像系统（0．15T）对足月顺产的正常新生儿20例和临床诊断的HIE患儿90例进行检查。HIE组病人的临床分度分别是轻度40例、中度38例和重度12例。结果：正常组新生儿的脑灰白质对比清楚，以T2加权像最明显。HIE组病人脑内均有片状的异常信号病灶，T1加权像为低信号，T2加权像为高信号，均伴有皮层灰质与白质的对比模糊或消失；83例见于2个脑叶以上；86例呈对称分布。26例见蛛网膜下脑出血，20例见白质病灶内出现点片状出血。结论：MRI对新生儿HIE的诊断有重要意义。

MRI Diagnosis of Neonatal Hypoxic Ischemic Encephalopathy

Purpose: To study the manifestation of MR imaging of neonatal hypoxic ischemic encephalopathy (HIE).Meterials and Methods: MR imaging was done with 0.15T MR scanner in 20 term birth normal neonates and in 90 neonatal HIE patients which were classified as mild (40 cases), moderate (38 cases) and sever degrees (12 cases) based on clinical manifestation. Results: In all patients, the lesion were showed in cerebrum which appeared hypointense on T1-weighted images and hyperintense on T2 - weighted images with indistinct coctrast between white matter and cerebral cortex.The lesions were found out in more than 2 braim Lobes in 83 cases and symmetrized in 86 cases. Subarachnoid hemorrhage and patch hemorrhage in the lesions of white matter were seen respectively in 26 and 20 patients. Conclusion: MR imaging can provide valuable guide for the diagnosis and therapy of neonatal HIE.