新生儿窒息后脑损伤B超诊断及相关因素的临床研究

目的探讨新生儿脑损伤与窒息的相关性。方法选取2006年10月~2007年4月在我院出生的132例新生儿,其中早产儿67例,足月儿65例,全部进行颅脑B超检查,并整理、分析相关的临床资料。结果132例新生儿病例中,脑损伤36例,其中早产儿27例,占早产儿的40.3%(27/67),足月儿脑损伤9例,占足月儿的13.8%(9/65)。低出生体重儿脑损伤23例,占低出生体重儿的41.4%(23/56),正常出生体重儿脑损伤13例,占正常出生体重儿17.1%(13/76)。早产儿、低出生体重儿颅脑损伤发生率分别较足月儿、正常出生体重儿明显升高,统计学有明显差异(P<0.01,P<0.05),早产儿、低出生体重儿脑损伤在对照组与窒息组间比较无明显差异(P>0.05),而足月儿、正常出生体重儿在对照组、与窒息组间存在明显差异(P<0.05)。结论新生儿窒息是引起足月儿、正常出生体重儿脑损伤的主要因素。颅脑B超可对新生儿脑损伤作出早期诊断。

B-ULTRASONOGRAPHY IN DIAGNOSING CRANIOCEREBRAL INJURY OF NEWBORN WITH ASPHYXIA AND RELATED FACTORS

Objective To explore the correlation between craniocerebral injury and asphyxia.Methods B-ultrasonography was used to conduct craniocerebral examinations of 132 newborns including 67 premature ones and 65 full-term ones from October,2006 to April,2007.Results Of the 132 cases,36 suffered from craniocerebral injury.40.3%(27 cases) of the premature infants and 13.8%(9 cases) of the full-term ones were diagnosed with craniocerebral injury.The disease occurred in 23 cases of low birth weight newborns,accounting for 41.4%.13 normal birth weight newborns suffered from the disease,accounting for 17.1% of the normal ones.There existed significant differences in the rate of craniocerebral injury between premature,low birth weight newborns and the full-term and normal birth weight ones(P<0.01,P<0.05).No significant differences were found between the contrast group and the group of asphyxia(P>0.05) in terms of the craniocerebral injury of premature,low birth weight newborns,but significant differences was found between the contrast and asphyxia groups of full-term and normal newbrons(P<0.05).Conclusion Asphyxia is the major factor leading to craniocerebral injury in full-term,normal birth weight infants,and B-ultrasinography can be used to conduct early diagnosis of the disease.