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急性冠状动脉综合征患者血清C-反应蛋白的临床意义
引用本文:陈欣,郭素箴,党群,曹燕然. 急性冠状动脉综合征患者血清C-反应蛋白的临床意义[J]. 天津医药, 2003, 31(2): 88-89
作者姓名:陈欣  郭素箴  党群  曹燕然
作者单位:300192,天津市第一中心医院心内科
摘    要:目的 :探讨急性冠状动脉综合征 (ACS)患者血清C_反应蛋白 (CRP)的改变及其与冠状动脉粥样斑块稳定性的关系。方法 :用散射光比浊法测定65例ACS患者及50例对照组血清CRP含量 ,ACS组均行冠状动脉造影 (CAG)及血管内超声 (IVUS)检查 ,根据冠状动脉病变在血管内超声显像上的管壁横断面分布将ACS组又分为ACS1(同心性斑块 )和ACS2(偏心性斑块或血栓形成 )。结果 :ACS组CRP水平明显高于对照组 (P<0.01) ,ACS2组CRP水平明显高于ACS1组 (P<0.05)。结论 :炎症反应在ACS发病中起重要作用 ,CRP与动脉粥样硬化斑块的不稳定有关

关 键 词:急性冠状动脉综合征 临床意义 C反应蛋白质

Clinical Significance of Serum C-reactive Protein(CRP) in Patients with Acute Coronary Syndrome
CHEN Xin,GUO Suzhen,DANG Qun,CAO YanranFirst Central Hospital of Tianjin, China. Clinical Significance of Serum C-reactive Protein(CRP) in Patients with Acute Coronary Syndrome[J]. Tianjin Medical Journal, 2003, 31(2): 88-89
Authors:CHEN Xin  GUO Suzhen  DANG Qun  CAO YanranFirst Central Hospital of Tianjin   China
Affiliation:CHEN Xin,GUO Suzhen,DANG Qun,CAO YanranFirst Central Hospital of Tianjin,300192 China
Abstract:Objective:To study the serum level of C_reactive protein(CRP)in patients with acute coronary syndrome(ACS)and the relationship between CRP and the stability of coronary artherosclerosis plaque.Methods:Serum levels of CRP in 65 patients in ACS group were examined with coronary angiography(CAG)and intravascular ultrasound(IVUS).Results:The level of CRP in ACS group was significantly higher than that in control group(P<0.01).The level of GRP in ACS 2 group(eccentric plaque and/or thrombosis)was higher than that in ACS1 group(concentric plaque).Conclusion:Inflammation has an important effect in the development of ACS,CRP is relative to unstable lesion of plaque.
Keywords:C_reactive protein coronary disease acute disease syndrome  
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