清毒活血化痰复方治疗急性血管性痴呆临床疗效观察

目的 探讨清毒活血化痰复方（QDH）治疗急性血管性痴呆的疗效及安全性.方法 急性血管性痴呆患者100例,其中治疗组70例,对照组30例.治疗组采用清毒活血化痰复方治疗;对照组用尼莫地平治疗.治疗前后测定血中细胞间黏附分子（ICAM-1）,血脂,血液流变学.结果 治疗组综合疗效明显高于对照组（P＜0.01）,用清毒活血化痰复方治疗前后比较血中细胞间黏附分子表达下降.总胆固醇,三酸甘油脂,低密度脂蛋白下降,差异有统计学意义.血液粘稠度下降,差异有统计学意义.结论 清毒活血化痰复方对急性血管性痴呆患者具有较好的临床疗效,且安全性好.

Clinical observation of acute cerebral vascular dementia treated by incorporating QDH

Objective To investigate the therapeutic effect of incorporating QDH on acute cerebral vascular dementia(VD).Methods 100 patients with acute cerebral vascular dementia were randomly divided into treatment group of 70 patients and control group of 30 patients.The treatment group used incorporating QDH;The control group used nimodipine.It was 20 days on therapeutic course for 2 groups.Results The total effective rate in treatment group was 90%,which was 33% in control group respectively.There was a significant difference between two groups(P<0.01).After treatment there were significant difference in intercellular adhesion molecule-1(ICAM-1),low-density lipoprotein-cholesterol(LDL-C) in treatment group(P<0.05 or P<0.01).Conclusion Incorporating QDH can treat acute cerebral vascular dementia with good therapeutic efficacy and there is a safe effect.