1503例泌尿生殖道支原体感染及药敏结果分析

目的了解泌尿生殖系统支原体感染情况,感染人群中性别的分布及对11种抗菌药物的敏感性。方法支原体检测及药敏分析采用美国其昌达生物高科技(上海)有限公司生产的解脲脲支原体(Uu)和人支原体(Mh)培养鉴别定量药敏试剂盒。结果1503例泌尿生殖道感染患者支原体阳性757例,感染率为50.4%;其中解脲脲支原体感染率29.1%,人支原体感染率1.6%,Uu合并Mh感染率19.7%;男女性别感染率分别为40.6%和51.7%,经统计学处理,两者差异有统计学意义(P<0.01);药敏结果表明,米诺霉素、多西环素敏感度明显高于其他抗菌药物。结论支原体对各种抗菌药物已产生一定的耐药性,在治疗支原体感染时应参考药敏结果,如不能做药敏试验,则米诺霉素、多西环素可作为治疗支原体感染的首选药物。

Urogenital Tract Mycoplasma Infection and Its in vitro Susceptibility to Antibiotics:An Analysis of 1503 Cases

OBJECTIVE To know about the urogenital tract caused by Mycoplasma and their variation by sex as well as the sensitivities to the 11 antimicrobials.METHODS The Ureaplasma urealyticum(Uu) and Mycoplasma hominis(Mh) CICS reagent kit was adopted,and the mycoplasma isolates were cultivated and identified,and the drug sensitivity test was conducted.RESULTS Among the 1503 samples,757 were positive(50.4%),which were composed by Uu 29.1%,Mh 1.6%,and Uu-Mh infection 19.7%.Among 1323 females,684 were positive(51.7%);among 180 males,73 were positive(40.6%);females were more apt to be infected according to the statistics(P<0.01).According drug sensitivity test results,minomycin and doxycyline were more sensitive than the other antibiotics.CONCLUSIONS Mycoplasma produce particular resistance to antibiotics.They should rationally choose and use according to the drug susceptibility.If they cannot do drug sensitivity test,they should choose minomycin and doxycycline as the main drugs.