两种内固定物置入增强前路椎间融合后腰椎即刻稳定性的差异

背景：腰椎前路自锁定椎间融合器SynFix-LR与前路钢板和后路椎弓根螺钉比较，其操作更简单、创伤更少，而且其前方0切迹设计降低了血管损伤的风险。如果前路椎间融合后以SynFix-LR固定与后路椎弓根螺钉固定在生物力学上相似，那么在避免后路手术入路的情况下就可以达到同样的脊柱稳定的效果。目的：比较前路椎间融合后以前路自锁定椎间融合器固定和后路椎弓根螺钉固定后腰椎即刻稳定性的差异。方法：选用15具新鲜小牛腰椎标本，模拟临床建立前路椎间融合后SynFix-LR固定模型和后路椎弓根螺钉内固定模型，在脊柱三维运动测试机上测试两种内固定模型生物力学特性上差异。结果与结论：行单纯前路椎间融合后，腰椎的稳定性比完整标本有明显的下降。以SynFix-LR固定和后路椎弓根螺钉固定都能有效地增加腰椎前路椎间融合的初始稳定性，而且两种固定增加脊柱稳定性的效果之间在统计学上没有显著性区别，因此认为SynFix-LR是较理想的前路椎间融合固定器械，可以在一定范围内用于临床。

Difference in immediate stabilization of the lumbar vertebra between two internal fixities for enhancing anterior lumbar interbody fusion

BACKGROUND: Compared with anterior plate and posterior pedicle screw, anterior lumbar vertebrae self-locking interbody fusion cage SynFix-LR is characterized by simple operation and small trauma. Moreover, the design of 0 incisure in the front decreases the risk for damage to blood vessel. If SynFix-LR fixation is similar to posterior pedicle screw in biomechanics following anterior vertebral fusion, the same efficiency of spinal stabilization can be achieved with the exception of posterior operative approach. OBJECTIVE: To compare the differences in spinal stabilization of lumbar vertebra between two types of internal fixation techniques (SynFix-LR and posterior pedicle screw). METHODS: A total of 15 fresh bovine lumbar vertebra samples were selected to simulate SynFix-LR and posterior pedicle screw fixation models following anterior interbody fusion. The differences in biomechanics between two types of models were compared using spinal column three-dimensional movement tester. RESULTS AND CONCLUSION: Following simple anterior interbody fusion, the stabilization of lumbar vertebra was significantly reduced compared with integral samples. SynFix-LR fixation and posterior pedicle screw fixation could effectively increase the initial stabilization of anterior lumbar vertebra interbody fusion. There was no significant difference in efficiency of increasing spinal stabilization between the two methods. Thus, SynFix-LR should be considered as an ideal option for interbody fusion, and can be used in clinic.