| 脂质体包封血红蛋白体外对血液流变性影响的研究 |
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| 引用本文： | 王怡,刘剑刚,许秀森,李白霞,邓百鸣.脂质体包封血红蛋白体外对血液流变性影响的研究[J].中国血液流变学杂志,1994(3). |
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| 作者姓名： | 王怡 刘剑刚 许秀森 李白霞 邓百鸣 |
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| 作者单位： | 中国中医研究院西苑医院!(北京100091)(王怡，刘剑刚，许秀森)，北京理工大学应用化学系!(北京)(李白霞，邓百鸣) |
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| 摘 要： | 本文对脂质体包封血红蛋白（LEH）体外对血液流变性影响进行初步研究。观察了几种不同磷脂组成和配比的脂质体与 LEH对体外血栓形成、血液粘度和红细胞聚集指数的影响。研究发现，ＬＥＨ能使血液粘度降低，并可改善红细胞聚集指数，ＬＥＨ加入到血液中不会导致血栓形成，尚有轻微减缓体外血栓形成作用。
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| 关 键 词： | 脂质体包封血红蛋白(LEH) 血液流变性 |
EFFECT OF LIPOSOMES-ENCAPSULATED HEMOGLOBIN ON HEMORHEOLOGICAL INDICES IN VITRO |
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| Yi Wang Jiangang Liu Xiusen Xu Weiliang Weng Xi Yuan Hospital,Academy of Traditional Chinese Medicine,Beijing Baixia Deng Baiming Deng Caoming Sun Applied Chemistry.EFFECT OF LIPOSOMES-ENCAPSULATED HEMOGLOBIN ON HEMORHEOLOGICAL INDICES IN VITRO[J].Chinese Journal of Hemorheology,1994(3). |
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| Authors: | Yi Wang Jiangang Liu Xiusen Xu Weiliang Weng Xi Yuan Hospital Academy of Traditional Chinese Medicine Beijing Baixia Deng Baiming Deng Caoming Sun Applied Chemistry |
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| Institution: | Yi Wang Jiangang Liu Xiusen Xu Weiliang Weng Xi Yuan Hospital,Academy of Traditional Chinese Medicine,Beijing 100091 Baixia Deng Baiming Deng Caoming Sun Applied Chemistry Department,Beijing College of Science and Engineering |
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| Abstract: | In this paper, we studied the possibilities of using LEH as blood substitute, Preliminary studies have done on the influence of some kinds of liposomes and LEH on thrombus formation in vitro, blood viscosity and erythrocyte gathering properties. The study found that LEH can decrease the blood viscosity, improve erythrocyte gathering properties , and LEH can not only induce thrombosis, but also reduce thrombus formation in vitro. |
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| Keywords: | Liposomes-encapsulated Hemoglobin Hemorheological |
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