| 他克莫司软膏治疗局限性慢性单纯性苔藓临床观察 |
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| 引用本文： | 杨建强,宋颖劼.他克莫司软膏治疗局限性慢性单纯性苔藓临床观察[J].中国药房,2010(10):915-916. |
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| 作者姓名： | 杨建强 宋颖劼 |
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| 作者单位： | [1]湖州师范学院医学院,湖州市313000 [2]浙江湖州市中心医院皮肤科,湖州市313000 |
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| 摘 要： | 目的:观察他克莫司软膏治疗局限性慢性单纯性苔藓的临床疗效和安全性。方法:70例局限性慢性单纯性苔藓患者随机分为2组,治疗组35例,患处涂抹0.03%他克莫司软膏;对照组35例,患处涂抹0.05%卤米松乳膏。用法均为每日2次,疗程均为4周。结果:治疗组与对照组总有效率分别为88.2%、90.9%,不良反应发生率分别为17.6%、12.1%,2组比较差异均无统计学意义(P>0.05)。结论:他克莫司软膏治疗局限性慢性单纯性苔藓较为安全、有效。
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| 关 键 词： | 慢性单纯性苔藓 他克莫司 卤米松 |
Efficacy and Safety of Tacrolimus Ointment for Patients with Local Lichen Simplex Chronicus |
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| YANG Jian-qiangThe Medical School of Huzhou Normal College,Huzhou,China SONG Ying-.Efficacy and Safety of Tacrolimus Ointment for Patients with Local Lichen Simplex Chronicus[J].China Pharmacy,2010(10):915-916. |
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| Authors: | YANG Jian-qiangThe Medical School of Huzhou Normal College Huzhou China SONG Ying- |
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| Institution: | YANG Jian-qiang(The Medical School of Huzhou Normal College, Huzhou 313000, China) SONG Ying-jie(Dept. of Dermatology, Zhejiang Huzhou Central Hospital, Huzhou 313000, China) |
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| Abstract: | OBJECTIVE： To observe the clinical efficacy and safety of Tacrolimus Ointment in the treatment of local lichen simplex chronicus. METHODS： A total of 70 patients with local lichen simplex chronicus were randomly divided into two groups： 35 in the trial group were locally applied with 0.03% Tacrolimus Ointment b.i.d, and another 35 in the control group were locally applied with 0.05 % Halometasone Cream b.i.d. The course of treatment was 4 weeks for both groups. RESULTS： There were no significant differences between the trial group and the control group in total effective rate（88.2% vs. 90.9% ,P〉0.05） and the incidence of adverse effects （ 17.6 % vs. 12.1%, P〉0.05）. CONCLUSION： Comparatively speaking, Tacrolimus Ointment is safe and effective for local lichen simplex chronicus. |
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| Keywords: | Lichen simplex chronicus Tacrolimus Halometasone |
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