女性急性冠状动脉综合征患者焦虑抑郁情绪研究

目的探讨女性急性冠状动脉综合征（ACS）患者焦虑、抑郁情绪发生情况。方法连续入选2011年1月至2012年1月北京安贞医院心内科住院ACS患者386例，采用医院焦虑抑郁评分量表进行心理测评，评价焦虑、抑郁及共病的发生率。结果262例男性ACS患者中，65例（24．8％）存在焦虑情绪，54例（20．6％）存在抑郁情绪，39例（14．9％）存在焦虑抑郁共病；124例女性ACS患者中，66例（53．2％）存在焦虑情绪，48例（38．7％）存在抑郁情绪，33例（26．6％）存在焦虑抑郁共病。女性焦虑、抑郁、焦虑抑郁共病发生率明显高于男性，差异均有统计学意义（均P〈0．01）。报销比例≤40％、月收入〈1000元是女性ACS患者发生抑郁的主要影响因素（OR=6．216、2．672，95％CI：1．229～5．583和1．161～6．150，均P〈0．05）。结论对于并发焦虑抑郁情绪的女性ACS患者，应引起临床医师重视，尽早给予心理干预，改善预后。

Anxiety and depression in female patients with acute coronary syndrome

Objective To investigate prevalences of anxiety and depression in female patients with acute coronary syndrome（ACS）. Methods All 386 patients with ACS that admitted in our hospital from January 2011 to January 2012 were collected. All the subjects were assessed with hospital anxiety and depression scale. The incidences of anxiety, depression and eomorbidity of anxiety and depression were evaluated. Results Of all male patients, 65 cases （24.8%） were identified as anxiety, 54 cases （20.6%） were depression and 39 cases （ 14. 9% ） were comorbidity of anxiety and depression. Of all female patients, 66 cases （53.2%） were identified as anxiety, 48 cases （38.7%） were depression, 33 cases （26.6%） were eomorbidity of anxiety and depression. There were significant differences in incidence of anxiety, depression and eomorbidity between female and male patients of ACS. The medical reimbursements〈40% and monthly income 〈 1000 yuan were the main factors on depression visibility （0R=6.216, 2.672, 95% CI： 1.229-5.583 and 1. 161-6. 150, P〈0.05）. Conclusion There exists high prevalence of anxiety and depression disorders with female ACS patients.