Identification of subpopulations of lymphocytes and macrophages in the infiltrate of lichen planus lesions of skin and oral mucosa |
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Authors: | D.M. WALKER |
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Affiliation: | Department of Oral Medicine and Oral Pathology, Welsh National School of Medicine, University Hospital of Wales, Cardiff. |
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Abstract: | The mononuclear cells of the infiltrate in lichen planus lesions of skin and oral mucosa have been identified by detection of their membrane receptors in frozen-tissue sections. By this method, the infiltrate would appear to consist of predominantly T lymphocytes, some macrophages and only a few B cells. The pathogenesis of lichen planus is discussed in the light of these findings. |
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