早发型重度子痫前期期待治疗对妊娠结局的影响

目的 探讨期待治疗不同孕周早发型重度子痫前期对母儿结局的影响.方法 对158例不同孕周的早发型重度子痫前期患者进行回顾性分析.根据发病孕周分成A组(孕周<28周)28例、B组(28周≤孕周<32周)51例、C组(32周≤孕周<34周)79例.结果 B组期待治疗的时间(15±5)d显著长于其他两组(P<0.05);B组、C组分娩方式以剖宫产为主;三组间患者并发症发生率差异无统计学意义(P>0.05);三组问新生儿窒息发生率及围生儿死亡率差异有统计学意义(P<0.05),随着孕周延长而下降.结论 早发型重度子痫前期患者孕周越小,母儿并发症率、新生儿患病率及死亡率越高.

Analysis of the impact of early severe pre-eclampsia on outcome of gestation

Objective To investigate the effect of expectant management on the maternal and/or infant out-comes of early onset severe preeclamp sia in different gestafional weeks. Methods A retrospective study was carried out on 158 patients with early onset severe preeclampsia. They were divided into three groups according to their onset gestation ago:group A( <28weeks,n=28) ,group B(≥28、<32weeks,n=51) and group C(≥32、< 34weeks,n =79). Results The rates of complications declined along with the postponement of the onset gestation age, but there was no statistical significant difference among these three groups. The neonatal asphyxia rate and perinatal infant mor-tality of these three groups declined along with the postponement of gestation age, and there were statistical significant differences among these three groups ( P<0.05 ). Expectant treatment time of group B was significantly longer than that of the other two groups ( P<0.05 ), and cesarean section was a main method of pregnancy termination for the groups B and C. Conclusion The smaller the gestational ages in the early onset severe preeelampsia,the higher the maternal and/ or infant complication rates, neonatal morbidity and mortality.