美蓝标记定位在椎管内肿瘤手术中的应用

目的探讨术前美蓝标记定位并照片在椎管内肿瘤手术中的应用价值。方法回顾性分析2010年9月至2012年9月我院收治的84例椎管内肿瘤患者的临床资料。依据患者是否采用美蓝标记定位椎管内肿瘤分为标记组和对照组。比较2组患者手术时间、术中出血、肿瘤全切率、脊柱不稳率、肿瘤复发率、再手术率。结果标记组患者手术时间显著短于对照组患者，术中出血显著少于对照组患者，P〈0．05具有统计学意义；标记组患者肿瘤全切率显著高于对照组患者，P〈0．05具有统计学意义。2组患者术后1年内脊柱不稳率、肿瘤复发率及再手术率上比较差异均无统计学意义。结论美蓝标记定位简单方便，为手术切除提供了有利条件，减少了手术时间及术中出血量，增加了肿瘤全切除率。

Application of methylene blue staining in operation of intraspinal tumors

Objective To explore the application value of preoperative methylene blue staining in locating for the operation of intraspi-al tumors. Methods The clinical data of patients with intraspinal tumors from September 2010 to September 2012 in our hospital were ret- rospectively analyzed. The patients were divided into tag group and control group according to whether stained by methylene blue or not. The operation time （ min）, intraoperative hemorrhage, the rate of total resection of tumor, spinal instability rate, tumor recurrence rate, and reopera-tion rate of two groups were compared. Results The operation time of tag group was significantly shorter than that of the control group. The amount of intraoperative bleeding was significantly less than that of in control group, the differences were statistically significant（ P 〈 0.05 ）. The total resection rate of tumor was significantly higher than that in control group, the differences were statistically significant （ P 〈 0.05 ）. The spinal instability rate, tumor recurrence rate and operation rate of patients within 1 year in two groups were not significant. Conclusion The methylene blue method is simple and convenient, and provides favorable conditions for the operation, which reduces the operation time and intraoperative hemorrhage, increases the rate of complete tumor resection. There was no difference in recurrence rate, operation rate and the stability of the spine within 1 year compared to traditional method.