| 厄贝沙坦治疗老年高血压左室舒张功能障碍的临床疗效观察 |
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| 引用本文： | 陈柏兴.厄贝沙坦治疗老年高血压左室舒张功能障碍的临床疗效观察[J].中南药学,2004,2(2):113-114. |
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| 作者姓名： | 陈柏兴 |
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| 作者单位： | 湖南省邵阳市中心医院,邵阳,422000 |
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| 摘 要： | 目的观察厄贝沙坦治疗老年高血压左室舒张功能障碍(LVDD)的疗效.方法 38例老年高血压LVDD 患者连续应用厄贝沙坦150 mg·d-16个月,并于治疗前后测定左室舒张功能,测量左房内径(LAD)、左室舒张末内径(LVDd)、左室射血分数(LVEF)、舒张早期峰值流速(VE)、心房收缩期峰值流速(VA)、E/A比值.结果 LAD、LVDd和VA下降(P＜0.01),LVEF、VE和E/A上升(P＜0.01).结论厄贝沙坦可明显改善老年高血压左室舒张功能障碍患者左室舒张功能.
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| 关 键 词： | 厄贝沙坦 原发性高血压 左室外舒张功能障碍 |
| 文章编号： | 1672-2981(2004)02-0113-02 |
Effect of irbesartan on treating left ventricular diastolic dysfunction in old patients with hypertension |
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| Chen Bai-xing.Effect of irbesartan on treating left ventricular diastolic dysfunction in old patients with hypertension[J].Central South Pharmacy,2004,2(2):113-114. |
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| Authors: | Chen Bai-xing |
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| Abstract: | OBJECTIVE To investigate the influence of irbesartan on left ventricular diastolic dysfunction (LVDD) in old hypertensive patients. METHODS Thirty-eight old hypertensive patients with LVDD were treated with irbesartan 150 mg orally once a day for 6 months. We determined the left ventricular diastolic function before and after the treatment. Left atrium diameter (LAD), left ventricular end diastolic diameter (LVDd), left ventricular ejection fraction (LVEF), E peak velocity (VE), A peak velocity (VA) and E/A were measured RESULTS After the treatment, LAD. LVDd and VA decreased significantly (P<0. 01), while LVEF VE and E/A increased significantly (P< 0. 01). CONCLUSIONS Irbesartan may improve the left ventricular diastolic function in old hypertensive patients with LVDD. |
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| Keywords: | irbesartan essential hypertension left ventricular diastolic dysfunction |
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