磁共振弥散张量成像在脑肿瘤放射治疗中的应用

弥散张量成像(diffusion tensor imaging,DTI)利用水分子弥散运动描述大脑空间结构,获得脑肿瘤的浸润破坏情况,使得疾病的诊断方式实现从宏观至微观、从形态学上升至形态与代谢并重,为脑肿瘤的诊疗研究带来新的机遇。在这篇综述中,概述了DTI技术的理论基础及目前的局限性,并对其在脑肿瘤放射治疗及其疗效预判中的应用价值进行全面讨论。DTI为脑肿瘤的放疗方案制定提供重要的影像学信息。

Application of diffusion tensor imaging to brain tumors radiotherapy

Diffusion tensor imaging (DTI) uses the diffusion motion of water molecules to describe the spatial structure of brain. DTI, which can obtain the infiltration of brain tumors into normal physiological structures, makes the diagnosis of diseases change from macroscopic to microscopic, from morphology to both morphology and metabolism, bringing new opportunities for the diagnosis and treatment of brain tumors. In this review, we outlined the theoretical basis and current technical limitations of DTI, and comprehensively discussed its research values in brain tumors radiotherapy treatment and its prognostic value. We believe that DTI can provide important imaging information for radiotherapy planning of brain tumors.