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柴胡产地加工及炮制方法研究进展
引用本文:刘德鹏,王云,张雪,王清浩,王国有,夏梦雨,麻印莲,雷振宏,王玉龙,张村,王成永. 柴胡产地加工及炮制方法研究进展[J]. 中国实验方剂学杂志, 2019, 25(19): 204-211
作者姓名:刘德鹏  王云  张雪  王清浩  王国有  夏梦雨  麻印莲  雷振宏  王玉龙  张村  王成永
作者单位:中国中医科学院 中药研究所, 北京 100700;安徽中医药大学 药学院, 合肥 230012,中国中医科学院 中药研究所, 北京 100700,中国中医科学院 中药研究所, 北京 100700,中国中医科学院 中药研究所, 北京 100700;河南中医药大学 药学院, 郑州 450008,中国中医科学院 中药研究所, 北京 100700;河南中医药大学 药学院, 郑州 450008,中国中医科学院 中药研究所, 北京 100700;河南中医药大学 药学院, 郑州 450008,中国中医科学院 中药研究所, 北京 100700,山西振东道地药材开发有限公司, 山西 长治 047100,山西振东道地药材开发有限公司, 山西 长治 047100,中国中医科学院 中药研究所, 北京 100700;安徽中医药大学 药学院, 合肥 230012;河南中医药大学 药学院, 郑州 450008,安徽中医药大学 药学院, 合肥 230012
基金项目:国家中药标准化项目(ZYBZH-Y-JIN-34);中国中医科学院自主选题项目(ZXKT16001)
摘    要:柴胡是临床常用的一种中药材,具有疏散退热、疏肝解郁、升举阳气的功效。目前,我国柴胡品种较为混乱,产地加工较为粗放;在柴胡炮制方面,2015年版《中国药典》收载的炮制品为柴胡生品及醋柴胡,除此之外,各省市炮制规范还收载了酒制、蜜制、鳖血制等方法,但各省市炮制规范存在较大的差异,如辅料种类及用量、炮制终点的判定标准等,致使以其为依据生产的柴胡饮片质量参差不齐,进而影响柴胡饮片的临床应用。笔者通过查阅古籍资料及相关文献,对柴胡品种进行考证,并对其产地加工方法和炮制方法等进行系统的归纳与总结,以期为柴胡饮片的炮制工艺规范及质量标准制定提供参考依据。

关 键 词:柴胡  产地加工  皂苷类  药理作用  炮制工艺  炮制规范  化学成分
收稿时间:2018-12-12

Research Progress of Processing in Production Place and Processing Methods of Bupleuri Radix
LIU De-peng,WANG Yun,ZHANG Xue,WANG Qing-hao,WANG Guo-you,XIA Meng-yu,MA Yin-lian,LEI Zhen-hong,WANG Yu-long,ZHANG Cun and WANG Cheng-yong. Research Progress of Processing in Production Place and Processing Methods of Bupleuri Radix[J]. China Journal of Experimental Traditional Medical Formulae, 2019, 25(19): 204-211
Authors:LIU De-peng  WANG Yun  ZHANG Xue  WANG Qing-hao  WANG Guo-you  XIA Meng-yu  MA Yin-lian  LEI Zhen-hong  WANG Yu-long  ZHANG Cun  WANG Cheng-yong
Affiliation:Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China;College of Pharmacy, Anhui University of Chinese Medicine, Hefei 230012, China,Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China,Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China,Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China;College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450008, China,Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China;College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450008, China,Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China;College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450008, China,Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China,Shanxi Zhendong Genuine Medicinal Materials Development Co. Ltd., Changzhi 047100, China,Shanxi Zhendong Genuine Medicinal Materials Development Co. Ltd., Changzhi 047100, China,Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China;College of Pharmacy, Anhui University of Chinese Medicine, Hefei 230012, China;College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450008, China and College of Pharmacy, Anhui University of Chinese Medicine, Hefei 230012, China
Abstract:Bupleuri Radix is a traditional Chinese medicine commonly used in clinical practice, which has the effects of relieving fever, relieving liver and depression, and promoting Yangqi. At present, the varieties of Bupleuri Radix are relatively chaotic, and the processing in the production areas is relatively extensive. In the processing of Bupleuri Radix, the processed products contained in the 2015 edition of Chinese Pharmacopoeia are raw products and vinegar-processed products. In addition, the specifications on Chinese medicine processing in various provinces and cities contain many processing methods, such as stir-frying with wine, stir-frying with honey, processed with turtle blood, etc. However, there are great differences in processing specifications among provinces and cities, and the processing methods lack clear process parameters, so the quality of Bupleuri Radix decoction pieces produced on these basis is uneven, which affects the clinical application of the decoction pieces. By consulting ancient books and relevant literature, the authors conduct textual research on the varieties of Bupleuri Radix, and systematically summarized the processing methods and processing methods in the producing area, so as to provide reference for the establishment of processing technology specifications and quality standards of Bupleuri Radix decoction pieces.
Keywords:Bupleuri Radix  processing in production place  saponins  pharmacological effects  processing technology  processing specifications  chemical compositions
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