| 经皮穴位电刺激对胸腔镜肺叶切除术患者围手术期炎症反应的影响 |
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| 引用本文： | 孔建强,冯 迪,陈原丽,闵屹华,汪建胜,吕 欣.经皮穴位电刺激对胸腔镜肺叶切除术患者围手术期炎症反应的影响[J].同济大学学报(医学版),2019,40(3):321-325. |
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| 作者姓名： | 孔建强 冯 迪 陈原丽 闵屹华 汪建胜 吕 欣 |
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| 作者单位： | 同济大学附属上海市肺科医院麻醉科，上海 200433；上海市宝山区中西医结合医院，上海 201999,同济大学附属上海市肺科医院麻醉科，上海 200433,同济大学附属上海市肺科医院麻醉科，上海 200433,同济大学附属上海市肺科医院麻醉科，上海 200433,上海市宝山区中西医结合医院，上海 201999,同济大学附属上海市肺科医院麻醉科，上海 200433 |
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| 基金项目： | 上海市科学技术委员会引导项目（14401932500）；上海市科学技术委员会产学研医合作项目（16DZ1930307） |
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| 摘 要： | 目的 研究经皮穴位电刺激对胸腔镜肺叶切除术患者炎性反应的影响。方法 选择在电视辅助胸腔镜下行肺叶切除术的患者60例，随机分为经皮穴位电刺激（transcutaneous electrical acupoint stimulation, TEAS）组和假经皮穴位电刺激组（Sham组），每组30例。TEAS组于麻醉诱导前30min经皮穴位电刺激双侧合谷穴、内关穴、后溪穴及支沟穴，电刺激持续至手术结束。Sham组于上述穴位贴电极片，但不给予电刺激。分别于手术前30min（T1）、单肺通气1h（T2）、手术结束后双肺通气10min（T3)及术后24h（T4)采集颈内静脉血，用流式细胞术检测血清IL-6、IL-10、TNF-α浓度；记录术后3d内的肺部并发症发生率、术后拔除胸管时间和平均住院日。结果 与Sham组比较，TEAS组血清IL-6及IL-10浓度在手术结束双肺通气10min时均显著降低（P＜0.05）；组内比较，两组患者血清IL-6及IL-10水平在手术结束双肺通气10min时均高于术前（P＜0.05）；两组术后肺部并发症、胸管拔除时间及平均住院日差异无统计学意义。结论 经皮穴位电刺激可降低全身麻醉下胸腔镜肺叶切除术患者术中炎性因子的表达，可能对胸腔镜肺叶切除术患者围手术期肺保护存在积极作用。
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| 关 键 词： | 经皮穴位电刺激 胸腔镜肺叶切除术 炎症反应 肺损伤 |
| 收稿时间： | 2019/5/1 0:00:00 |
Effects of transcutaneous electrical acupoint stimulation on inflammation in patients undergoing video-assisted thoracoscopic lobectomy |
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| KONG Jian-qiang,FENG Di,CHEN Yuan-li,MIN Yi-hu,WANG Jian-sheng and Lv Xin.Effects of transcutaneous electrical acupoint stimulation on inflammation in patients undergoing video-assisted thoracoscopic lobectomy[J].Journal of Tongji University(Medical Science),2019,40(3):321-325. |
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| Authors: | KONG Jian-qiang FENG Di CHEN Yuan-li MIN Yi-hu WANG Jian-sheng and Lv Xin |
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| Institution: | Dept. of Anesthesiology, Shanghai Pulmonary Hospital, Tongji University, Shanghai 200433, China; Dept. of Anesthesiology, Shanghai Baoshan Hospital of Integrated Traditional Chinese Medicine and Western Medicine, Shanghai 201999, China,Dept. of Anesthesiology, Shanghai Pulmonary Hospital, Tongji University, Shanghai 200433, China,Dept. of Anesthesiology, Shanghai Pulmonary Hospital, Tongji University, Shanghai 200433, China,Dept. of Anesthesiology, Shanghai Pulmonary Hospital, Tongji University, Shanghai 200433, China,Dept. of Anesthesiology, Shanghai Baoshan Hospital of Integrated Traditional Chinese Medicine and Western Medicine, Shanghai 201999, China and Dept. of Anesthesiology, Shanghai Pulmonary Hospital, Tongji University, Shanghai 200433, China |
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| Abstract: | |
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| Keywords: | transcutaneous electrical acupoint stimulation thoracoscopic lobectomy inflamm-ation lung injury |
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