| 白蔹生品与炮制品体外抗内毒素作用的比较研究 |
| |
| 引用本文： | 张少桦,孟飞,杨珊珊,宋学立.白蔹生品与炮制品体外抗内毒素作用的比较研究[J].药学实践杂志,2019,37(3):266-267. |
| |
| 作者姓名： | 张少桦 孟飞 杨珊珊 宋学立 |
| |
| 作者单位： | 解放军960医院淄博院区药剂科, 山东 淄博 255300,解放军960医院淄博院区药剂科, 山东 淄博 255300,解放军960医院淄博院区药剂科, 山东 淄博 255300,解放军960医院淄博院区药剂科, 山东 淄博 255300 |
| |
| 基金项目： | 原济南军区联勤部司令部课题（CJN15J052） |
| |
| 摘 要： | 目的 对白蔹生品与炮制品进行初步对比研究分析，拟筛选出白蔹体外对内毒素拮抗作用强的样品。方法 利用鲎试剂与内毒素产生凝集反应的原理，采用一系列不同浓度样品破坏凝集反应，以初步筛选白蔹体外抗内毒素的作用。结果 白蔹炮制品在浓度为1∶2 000时，体外仍有抗内毒素作用。结论 经炮制后白蔹的体外抗内毒素作用强于白蔹生品。
|
| 关 键 词： | 白蔹 炮制 抗内毒素 |
| 收稿时间： | 2018/11/22 0:00:00 |
| 修稿时间： | 2019/1/18 0:00:00 |
Comparative study on anti-endotoxins of crude and processed Ampelopsis radix in vitro |
| |
| ZHANG Shaohu,MENG Fei,YANG Shanshan and SONG Xueli.Comparative study on anti-endotoxins of crude and processed Ampelopsis radix in vitro[J].The Journal of Pharmaceutical Practice,2019,37(3):266-267. |
| |
| Authors: | ZHANG Shaohu MENG Fei YANG Shanshan and SONG Xueli |
| |
| Institution: | Department of Pharmacy, No. 960 Hospital of PLA, Zibo 255300, China,Department of Pharmacy, No. 960 Hospital of PLA, Zibo 255300, China,Department of Pharmacy, No. 960 Hospital of PLA, Zibo 255300, China and Department of Pharmacy, No. 960 Hospital of PLA, Zibo 255300, China |
| |
| Abstract: | Objective To screen the samples of stronger antagonism to anti-endotoxin in vitro from Ampelopsis radix through a preliminary comparative analysis on before and after processing of Ampelopsis radix.Methods The principle of agglutination produced by the limulus reagent and endotoxin was used.Different concentration samples were used to destroy the agglutination reaction so as to initially screen for the effect of in vitro anti-endotoxin.Results The processing products of Ampelopsis radix still had in vitro anti-endotoxin activity at the 1:2 000 concentration.Conclusion Ampelopsis radix after processing had stronger in vitro anti-endotoxin effect. |
| |
| Keywords: | Ampelopsis radix processed anti-endotoxins |
|
| 点击此处可从《药学实践杂志》浏览原始摘要信息 |
| 点击此处可从《药学实践杂志》下载免费的PDF全文 |
|
