| GPBB、cTnI、CK、CKMB在急性心肌梗死伴糖尿病早期诊断中的临床应用价值 |
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| 引用本文： | 秦小霞,武艳,张丽,靳萍奎,白雪梅,闫国超.GPBB、cTnI、CK、CKMB在急性心肌梗死伴糖尿病早期诊断中的临床应用价值[J].南华大学学报(医学版),2019(4):425-428. |
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| 作者姓名： | 秦小霞 武艳 张丽 靳萍奎 白雪梅 闫国超 |
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| 作者单位： | 河北医科大学第一医院检验科,河北 石家庄050031,河北医科大学第一医院检验科,河北 石家庄050031,河北医科大学第一医院检验科,河北 石家庄050031,河北医科大学第一医院急诊内科,河北 石家庄050031,河北医科大学第一医院检验科,河北 石家庄050031,河北医科大学第一医院检验科,河北 石家庄050031 |
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| 摘 要： | 分析心肌梗死伴糖尿病患者血清中糖原磷酸化酶同工酶BB(GPBB)、肌钙蛋白I (cTnI)、肌酸激酶(CK)、肌酸激酶同工酶(CKMB)水平的变化。结果显示糖尿病组、单纯急性心肌梗死组及急性心肌梗死伴糖尿病组患者血清中GPBB、cTnI、CK、CKMB、BNP及超敏C反应蛋白(Hs-CRP)水平明显升高(P<0.05),且急性心肌梗死伴糖尿病组患者与其他组相比差异均有显著性(P<0.05)；与GPBB、cTnI、CK、CKMB单独检测相比,各项目联合检测急性心肌梗死伴糖尿病敏感度和特异性均明显升高(P<0.05)。因此, GPBB、cTnI、CK、CKMB联合检测在急性心肌梗死伴糖尿病早期诊断中具有重要的参考价值。
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| 关 键 词： | 肌钙蛋白I 肌酸激酶 肌酸激酶同工酶 急性心肌梗死 糖尿病 早期诊断 |
| 收稿时间： | 2019/1/4 0:00:00 |
| 修稿时间： | 2019/4/28 0:00:00 |
The clinical value of GPBB, cTnI, CK and CKMB in early diagnosis of acute myocardial infarction with diabetes mellitus |
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| QIN Xiaoxi,WU Yan,ZHANG Li,JIN Pingkui,BAI Xuemei and YAN Guochao.The clinical value of GPBB, cTnI, CK and CKMB in early diagnosis of acute myocardial infarction with diabetes mellitus[J].Journal of Nanhua University(Medical Edition),2019(4):425-428. |
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| Authors: | QIN Xiaoxi WU Yan ZHANG Li JIN Pingkui BAI Xuemei and YAN Guochao |
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| Institution: | Department of Clinical Laboratory, Shijiazhuang 050031,Hebei,China,Department of Clinical Laboratory, Shijiazhuang 050031,Hebei,China,Department of Clinical Laboratory, Shijiazhuang 050031,Hebei,China,Department of Emergency Internal Medicine, The First Hospital of Hebei Medical University,Shijiazhuang 050031,Hebei,China,Department of Clinical Laboratory, Shijiazhuang 050031,Hebei,China and Department of Clinical Laboratory, Shijiazhuang 050031,Hebei,China |
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| Abstract: | The changes of serum levels of GPBB, cTnI, CK and CKMB in patients were analyzed. The Results showed that the serum levels of GPBB, cTnI, CK, CKMB, BNP and Hs-CRP in diabetic group, simple acute myocardial infarction group and acute myocardial infarction with diabetes mellitus group were significantly higher (P<0.05), and there were significant differences between acute myocardial infarction with diabetes mellitus group and other groups (P<0.05). Compared with GPBB, cTnI, CK, CKMB alone, the sensitivity and specificity of combined detection of acute myocardial infarction with diabetes mellitus were significantly increased (P<0.05). So The combined detection of GPBB, cTnI, CK and CKMB has important reference value in the early diagnosis of acute myocardial infarction with diabetes mellitus. |
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| Keywords: | troponin I creatine kinase creatine kinase isoenzyme acute myocardial infarction diabetes mellitus early diagnosis |
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