宁泌泰胶囊联合左氧氟沙星治疗慢性前列腺炎的疗效观察

目的:探讨宁泌泰胶囊联合左氧氟沙星对慢性前列腺炎患者炎症细胞的影响和临床症状改善的效果。方法:选取诊断为慢性前列腺炎的患者共160例,随机分为观察组和对照组各80例。对照组予以左氧氟沙星治疗,观察组予以宁泌泰胶囊联合左氧氟沙星治疗。比较两组治疗前后前列腺液中白细胞、和卵磷脂小体水平、NIH-CPSI评分和中医症候评分,评价两种用药方法对慢性前列腺炎患者的疗效。结果:两组治疗后前列腺液中白细胞计数和卵磷脂小体水平有显著改善,而NIH-CPSI各项评分和中医症候评分均比治疗前由显著下降(P<0.05),且观察组均显著低于对照组(P<0.05)。接受30d治疗后,观察组总有效率为77.50%,对照组为51.25%(P<0.05)。结论:与单一使用左氧氟沙星相比,采用宁泌泰胶囊联合左氧氟沙星治疗慢性前列腺炎,能够有效降低前列腺液炎症细胞水平,改善临床症状,提高治疗有效率。

Clinical Effect Observation of Ningmitai Capsules Combined with Levofloxacin in Treatment of Chronic Prostatitis

Objective To study the effect of Ningmitai Capsules combined with levofloxacin on inflammatory cells and clinical promotion outcomes of patients with chronic prostatitis. Methods Totally 160 patients with chronic prostatitis were involved in this study. They were randomly divided into two groups, the control group and the observation group. There were 80 patients in each group. Patients in the control group took only levofloxacin, while those in the observation group were given both Ningmitai Capsules and levofloxacin. White blood cells (WBC) and lecithin body (SPL) in prostate fluid, NIH-CPSI scores and symptom scores of traditional Chinese medicine (TCM) were compared between two groups before and after treatment. The clinical outcomes of two treatment methods were also compared. Results Patients in two groups had the improvement of WBC and SPL and the lower scores of NIH-CPSI and TCM symptoms after treatment compared with those before treatment (P<0.05). After treatment, the obvious improvement of WBC and SPL and lower scores of NIH-CPSI and TCM symptoms were obtained in the observation group than the control group (P<0.05). The total effective ratio in the observation group was 77.50%, which was much higher than that in the control group (51.25%, P<0.05). Conclusion The combination of Ningmitai Capsules and levofloxacin could effectively decrease the inflammatory cells in prostate fluid, improve the clinical features and increase the total effective rate when treating chronic prostatitis.